SCHEMBL8460934

SCHEMBL8460934

CC(=O)CC(=O)O/C(=C/C(=O)O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.43
GAA P10253 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
KDM4E B2RXH2 3/20 0.34
TSHR P16473 1/20 0.34
ALDH1A1 P00352 1/20 0.31
ATM Q13315 1/20 0.31
KDM6B O15054 1/20 0.30
KDM5C P41229 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30
PHF8 Q9UPP1 1/20 0.30
KDM2A Q9Y2K7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8460939 1.00 MGAM (0.43) MGAMGAASIMGAM2KDM4E
SCHEMBL7483442 0.87 KDM4E (0.39) KDM4ETSHR
SCHEMBL7483433 0.83 KDM4E (0.46) KDM4ETSHR
SCHEMBL7745871 0.76 TSHR (0.43) KDM4ETSHRALDH1A1ATM
SCHEMBL449524 0.72 MGAM (0.67) MGAMGAASIMGAM2KDM4E
SCHEMBL27303978 0.72 MGAM (0.52) MGAMGAASIMGAM2KDM4E
SCHEMBL542268 0.71 HCAR2 (0.40) KDM4ETSHRALDH1A1
SCHEMBL542266 0.71 HCAR2 (0.40) KDM4ETSHRALDH1A1
SCHEMBL28285219 0.71 MGAM (0.57) MGAMGAASIMGAM2KDM4E
SCHEMBL542267 0.71 HCAR2 (0.40) KDM4ETSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0795563-B1 Heat sensitizable latex GOODYEAR TIRE & RUBBER (US) 1999-12-29 EP disclosed
US-5804651-A Heat sensitizable latex THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-09-08 US disclosed
US-5780544-A Heat sensitizable latex THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-07-14 US disclosed
EP-0795563-A1 Heat sensitizable latex THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-09-17 EP disclosed