Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.41 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 5/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873575 | 0.92 | F2 (0.45) | F2ALDH1A1ITGB1ITGA4NTMT1 | |
| SCHEMBL845151 | 0.85 | ALDH1A1 (0.48) | ALDH1A1ITGB1ITGA4KDM1ARCOR1 | |
| SCHEMBL845158 | 0.84 | F2 (0.49) | F2ALDH1A1ITGB1ITGA4NTMT1 | |
| SCHEMBL845523 | 0.81 | POLB (0.59) | ALDH1A1KDM1ARCOR1POLBKDM4E | |
| SCHEMBL845226 | 0.80 | ALDH1A1 (0.56) | ALDH1A1ITGB1ITGA4KDM1ARCOR1 | |
| SCHEMBL15116912 | 0.80 | ALDH1A1 (0.56) | ALDH1A1ITGB1ITGA4KDM1ARCOR1 | |
| SCHEMBL845205 | 0.80 | ALDH1A1 (0.56) | ALDH1A1ITGB1ITGA4KDM1ARCOR1 | |
| SCHEMBL845111 | 0.80 | ALDH1A1 (0.56) | ALDH1A1ITGB1ITGA4KDM1ARCOR1 | |
| SCHEMBL13272444 | 0.80 | ALDH1A1 (0.56) | ALDH1A1ITGB1ITGA4KDM1ARCOR1 | |
| SCHEMBL1030175 | 0.80 | ALDH1A1 (0.56) | ALDH1A1ITGB1ITGA4KDM1ARCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |