SCHEMBL8460946

SCHEMBL8460946

C=C(C)c1cccc(C(=C)CC)c1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FURIN P09958 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
ALDH1A1 P00352 3/20 0.34
MAPT P10636 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
KDM4E B2RXH2 1/20 0.34
HTT P42858 2/20 0.33
LMNA P02545 2/20 0.33
ATM Q13315 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2260448 0.91 SMN1; SMN2 (0.38) FURINSMN1; SMN2L3MBTL1ATMTDP1
SCHEMBL167439 0.84 FURIN (0.43) FURINMAPTL3MBTL1HTTLMNA
SCHEMBL6252421 0.82 FURIN (0.41) FURINALDH1A1MAPTL3MBTL1KDM4E
SCHEMBL17421702 0.82 FURIN (0.41) FURINALDH1A1MAPTL3MBTL1KDM4E
SCHEMBL30834584 0.82 FURIN (0.41) FURINALDH1A1MAPTL3MBTL1KDM4E
SCHEMBL20863280 0.82 MAPT (0.33) FURINSMN1; SMN2ALDH1A1MAPTL3MBTL1
SCHEMBL3680344 0.81 MAOA (0.45) ALDH1A1MAPTATM
SCHEMBL18809537 0.80 KMT2A (0.49) SMN1; SMN2ALDH1A1MAPTL3MBTL1KDM4E
SCHEMBL15940011 0.79 FURIN (0.34) FURINSMN1; SMN2ALDH1A1MAPTL3MBTL1
SCHEMBL8444352 0.79 HPGD (0.50) SMN1; SMN2ALDH1A1MAPTTDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0700963-B1 Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines GOODYEAR TIRE & RUBBER (US) 1999-04-14 EP claimed
US-5726248-A ANTIOXIDANTS FOR DIENE POLYMERS WITH HIGH MOLECULAR WEIGHTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-03-10 US claimed
EP-0700963-A1 Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-03-13 EP claimed
EP-0446555-B1 Polymeric diphenyldiamines GOODYEAR TIRE & RUBBER (US) 1994-09-21 EP claimed
EP-0446555-A1 Polymeric diphenyldiamines THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-09-18 EP claimed
US-5049625-A Ozone resistant rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-09-17 US claimed
EP-0700963-B1 Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines GOODYEAR TIRE & RUBBER (US) 1999-04-14 EP disclosed
US-5726248-A ANTIOXIDANTS FOR DIENE POLYMERS WITH HIGH MOLECULAR WEIGHTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-03-10 US disclosed
EP-0700963-A1 Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-03-13 EP disclosed
EP-0446555-B1 Polymeric diphenyldiamines GOODYEAR TIRE & RUBBER (US) 1994-09-21 EP disclosed
EP-0446555-A1 Polymeric diphenyldiamines THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-09-18 EP disclosed
US-5049625-A Ozone resistant rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-09-17 US disclosed
EP-0122213-B1 PROCESS FOR MAKING POLYMERIC COMPOUNDS PREPARED FROM DIPHENYLAMINE AND DIALKYLALKENYLBENZENE OR DIHYDROXYALKYLBENZENE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1989-03-22 EP disclosed
US-4537952-A Polymeric compounds prepared from diphenylamine and dialkylalkenylbenzene or dihydroxyalkylbenzene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1985-08-27 US disclosed
EP-0122865-A1 Polymers with polymeric antioxidants prepared from diphenylamine and dialkylalkenylbenzene or dihydroxyalkylbenzene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-10-24 EP disclosed
EP-0122213-A1 Process for making polymeric compounds prepared from diphenylamine and dialkylalkenylbenzene or dihydroxyalkylbenzene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-10-17 EP disclosed
EP-0117831-A1 Stabilized polyester compositions THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-09-05 EP disclosed
US-4463170-A OXIDATION RESISTANCE STABILIZERS FOR POLYAMINES, POLYPHENYL RESINS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-07-31 US disclosed
US-4417017-A Polymeric antioxidants prepared from diphenyalmine and dialkylalkenylbenzene or dihydroxyalkylbenzene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-11-22 US disclosed
US-4414348-A POLYMERIC DIPHENYLAMINE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-11-08 US disclosed