SCHEMBL2260448

SCHEMBL2260448

C=C(CC)c1cccc(C(=C)CC)c1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.38
ATM Q13315 2/20 0.38
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
MAOA P21397 3/20 0.35
MAOB P27338 3/20 0.35
GAA P10253 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD17B10 Q99714 1/20 0.35
FURIN P09958 1/20 0.34
HPGD P15428 1/20 0.34
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8460946 0.91 FURIN (0.34) SMN1; SMN2ATMTDP1L3MBTL1KMT2A
SCHEMBL18809537 0.88 KMT2A (0.49) SMN1; SMN2TDP1L3MBTL1GAAKMT2A
SCHEMBL9627367 0.87 CA12 (0.47) SMN1; SMN2GAAHSD17B10
SCHEMBL4706020 0.87 C1S (0.48) L3MBTL1GAAKMT2AHPGD
SCHEMBL30313875 0.87 CA12 (0.47) SMN1; SMN2GAAHSD17B10
SCHEMBL8444352 0.87 HPGD (0.50) SMN1; SMN2TDP1KMT2AHPGDTAS1R3
SCHEMBL8464443 0.86 GAA (0.36) SMN1; SMN2ATML3MBTL1GAAKMT2A
SCHEMBL16687344 0.86 SMN1; SMN2 (0.32) SMN1; SMN2ATM
SCHEMBL25154801 0.85 F2 (0.47) SMN1; SMN2TDP1GAAKMT2AHSD17B10
SCHEMBL2015776 0.85 MAOA (0.48) MAOAMAOBGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0700963-B1 Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines GOODYEAR TIRE & RUBBER (US) 1999-04-14 EP claimed
US-5726248-A ANTIOXIDANTS FOR DIENE POLYMERS WITH HIGH MOLECULAR WEIGHTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-03-10 US claimed
EP-0700963-A1 Polymeric N-aryl substituted and N-alkaryl substituted diphenyldiamines THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-03-13 EP claimed
EP-0446555-B1 Polymeric diphenyldiamines GOODYEAR TIRE & RUBBER (US) 1994-09-21 EP claimed
EP-0446555-A1 Polymeric diphenyldiamines THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-09-18 EP claimed
US-5049625-A Ozone resistant rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-09-17 US claimed
EP-3231834-A1 METHOD FOR PRODUCING RUBBER COMPOSITION Bridgestone Corporation (JP) 2017-10-18 EP disclosed
US-20170240729-A1 METHOD FOR PRODUCING RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2017-08-24 US disclosed
EP-2110394-B1 PHOTOCURABLE LIQUID RUBBER COMPOSITION BRIDGESTONE CORP (JP) 2014-12-24 EP disclosed
EP-1953175-B1 METHOD FOR PRODUCING PHOTOCURABLE LIQUID RESIN AND PHOTOCURABLE LIQUID RESIN PRODUCED BY SUCH METHOD BRIDGESTONE CORP (JP) 2011-12-21 EP disclosed
US-20110190451-A1 PHOTOCURABLE LIQUID RESIN AND PHOTOCURABLE LIQUID RESIN PRODUCED BY SUCH METHOD BRIDGESTONE CORPORATION (JP) 2011-08-04 US disclosed
US-20100076107-A1 PHOTOCURABLE LIQUID RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2010-03-25 US disclosed
EP-2110394-A1 PHOTOCURABLE LIQUID RUBBER COMPOSITION Bridgestone Corporation (JP) 2009-10-21 EP disclosed
US-4537952-A Polymeric compounds prepared from diphenylamine and dialkylalkenylbenzene or dihydroxyalkylbenzene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1985-08-27 US disclosed
EP-0122865-A1 Polymers with polymeric antioxidants prepared from diphenylamine and dialkylalkenylbenzene or dihydroxyalkylbenzene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-10-24 EP disclosed
EP-0122213-A1 Process for making polymeric compounds prepared from diphenylamine and dialkylalkenylbenzene or dihydroxyalkylbenzene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-10-17 EP disclosed
EP-0117831-A1 Stabilized polyester compositions THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-09-05 EP disclosed
US-4463170-A OXIDATION RESISTANCE STABILIZERS FOR POLYAMINES, POLYPHENYL RESINS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-07-31 US disclosed
US-4417017-A Polymeric antioxidants prepared from diphenyalmine and dialkylalkenylbenzene or dihydroxyalkylbenzene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-11-22 US disclosed
US-4414348-A POLYMERIC DIPHENYLAMINE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-11-08 US disclosed