SCHEMBL8460972

SCHEMBL8460972

O=C(O)COP(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.48
PAM P19021 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
POLB P06746 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
GLA P06280 1/20 0.41
PTPN7 P35236 2/20 0.40
FFAR1 O14842 1/20 0.40
ALDH1A1 P00352 3/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
MAPT P10636 1/20 0.39
PTPN12 Q05209 1/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.39
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
AKR1B1 P15121 1/20 0.38
CD69 Q07108 2/20 0.37
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6860913 0.80 CYP3A4 (0.36) ALOX15L3MBTL1POLBSMN1; SMN2GLA
SCHEMBL3963406 0.74 CYP3A4 (0.43) ALDH1A1KDM4ETDP1GAA
SCHEMBL685567 0.71 ALDH1A1 (0.46) ALDH1A1KMT2AMEN1TDP1GAA
SCHEMBL1010756 0.71 ALDH1A1 (0.42) POLBSMN1; SMN2ALDH1A1MAPTKDM4E
SCHEMBL196443 0.70 CYP3A4 (0.39) L3MBTL1GLAALDH1A1TDP1
SCHEMBL5346768 0.70 CYP3A4 (0.39) TDP1
SCHEMBL13372616 0.70 ALDH1A1 (0.41) POLBSMN1; SMN2ALDH1A1MAPTKDM4E
SCHEMBL27261674 0.70 ALDH1A1 (0.41) POLBSMN1; SMN2ALDH1A1MAPTKDM4E
SCHEMBL10527995 0.70 ALDH1A1 (0.41) POLBSMN1; SMN2ALDH1A1MAPTKDM4E
SCHEMBL8678949 0.69 ALOX15 (0.53) ALOX15PAML3MBTL1POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5866087-A FROM AQUEOUS SOLUTIONS OF WASTE FUELS COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1999-02-02 US disclosed