SCHEMBL8458243

SCHEMBL8458243

C=CC(=O)OC(C)[Si](OCCCC)(OCCCC)OCCCC

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.51
HPGD P15428 1/20 0.51
THRB P10828 4/20 0.38
ATM Q13315 1/20 0.38
ALDH1A1 P00352 4/20 0.35
CYP3A4 P08684 1/20 0.35
HCAR2 Q8TDS4 2/20 0.34
THRA P10827 1/20 0.32
LMNA P02545 2/20 0.32
TP53 P04637 2/20 0.32
HIF1A Q16665 2/20 0.32
HSD17B10 Q99714 1/20 0.32
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8461587 0.90 TSHR (0.42) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL2476564 0.83 TSHR (0.41) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL136293 0.83 TSHR (0.50) TSHRHPGDTHRBATMALDH1A1
SCHEMBL10608002 0.80 ALDH1A1 (0.45) TSHRHPGDATMALDH1A1LMNA
SCHEMBL28471218 0.79 TSHR (0.46) TSHRHPGDTHRBATMALDH1A1
SCHEMBL8460675 0.77 TSHR (0.45) TSHRHPGDTHRBATMALDH1A1
SCHEMBL1132964 0.76 TSHR (0.46) TSHRHPGDTHRBATMALDH1A1
SCHEMBL1064311 0.75 TSHR (0.41) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL29249903 0.75 TSHR (0.49) TSHRHPGDTHRBATMALDH1A1
SCHEMBL27989551 0.75 TSHR (0.45) TSHRHPGDTHRBATMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108300385-B Adhesive sheet, display, and method for producing same 琳得科株式会社 2022-02-15 CN disclosed
EP-0604677-B1 Method of making coated shaped articles MITSUBISHI RAYON CO (JP) 1999-08-11 EP disclosed
US-5470616-A Coated shaped articles and method of making same MITSUBISHI RAYON CO., LTD. (JP) 1995-11-28 US disclosed
EP-0604677-A1 Coated shaped articles and method of making same MITSUBISHI RAYON CO., LTD. (JP) 1994-07-06 EP disclosed