Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8462452 | 0.77 | CES1 (0.45) | CES1SRCTSHRKMT2AL3MBTL1 | |
| SCHEMBL4953088 | 0.75 | SMN1; SMN2 (0.45) | CES1SRCTSHRKMT2AL3MBTL1 | |
| SCHEMBL1264958 | 0.75 | CES1 (0.44) | CES1SRCTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL15651 | 0.75 | CES1 (0.49) | CES1SRCTSHRKMT2AL3MBTL1 | |
| SCHEMBL28189546 | 0.75 | SRC (0.57) | CES1SRCTSHRKMT2ASMN1; SMN2 | |
| SCHEMBL6763904 | 0.74 | CES1 (0.47) | CES1SRCSMN1; SMN2GAAMLYCD | |
| Methane SCHEMBL16506198 | 0.73 | CES1 (0.47) | CES1SRCTSHRKMT2AL3MBTL1 | |
| SCHEMBL2124071 | 0.73 | CES1 (0.47) | CES1SRCTSHRKMT2AL3MBTL1 | |
| SCHEMBL31328399 | 0.73 | CES1 (0.47) | CES1SRCTSHRKMT2AL3MBTL1 | |
| SCHEMBL4591841 | 0.73 | CES1 (0.47) | CES1SRCGAALMNAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3536308-A1 | SKIN CARE PREPARATIONS | Nisshinbo Holdings Inc. (JP) | 2019-09-11 | — | — | EP | disclosed |
| US-20190254938-A1 | SKIN COSMETICS | NISSHINBO HOLDINGS INC. (JP) | 2019-08-22 | — | — | US | disclosed |
| EP-3185850-A1 | SKIN COLOR-IMPROVING AGENT AND COMPOSITION FOR IMPROVING SKIN COLOR | Showa Denko K.K. (JP) | 2017-07-05 | — | — | EP | disclosed |
| EP-2832727-B1 | NOVEL BENZYLIDENE AZOLIDINE DERIVATIVE OR SALT THEREOF | ROHTO PHARMA (JP) | 2016-09-07 | — | — | EP | disclosed |
| US-9422246-B2 | Benzylidene azolidine derivative or salt thereof | ROHTO PHARMACEUTICAL CO., LTD. (JP) | 2016-08-23 | — | — | US | disclosed |
| WO-2016031634-A1 | SKIN COLOR-IMPROVING AGENT AND COMPOSITION FOR IMPROVING SKIN COLOR | SHOWA DENKO K. K. (JP) | 2016-03-03 | — | — | WO | disclosed |
| US-20150065728-A1 | NOVEL BENZYLIDENE AZOLIDINE DERIVATIVE OR SALT THEREOF | ROHTO PHARMACEUTICAL CO., LTD. (JP) | 2015-03-05 | — | — | US | disclosed |
| EP-2832727-A1 | NOVEL BENZYLIDENE AZOLIDINE DERIVATIVE OR SALT THEREOF | Rohto Pharmaceutical Co., Ltd. (JP) | 2015-02-04 | — | — | EP | disclosed |
| EP-2516510-A1 | SURFACE-TREATMENT AGENT FOR POWDER FOR USE IN COSMETIC AND COSMETIC CONTAINING POWDER TREATED WITH THE SAME | Dow Corning Toray Co., Ltd. (JP) | 2012-10-31 | — | — | EP | disclosed |
| US-20100183529-A1 | Cosmetic compositions comprising photostabilized dibenzoylmethane compounds and 2-pyrrolidinone-4- carboxy esters | L'OREAL (FR) | 2010-07-22 | — | — | US | disclosed |
| US-20070041922-A1 | Compositions for Treating Keratinous Surfaces | CITICORP USA, INC. | 2007-02-22 | — | — | US | disclosed |
| US-20070020216-A1 | Compositions for Treating Keratinous Surfaces | REVLON CONSUMER PRODUCTS CORPORATION | 2007-01-25 | — | — | US | disclosed |
| US-20050118124-A1 | A foundation makeup, concealer, powder, eyeshadow, mascara, eyeliner, or blush with Acetyl Hexapeptide-3 as a primary ingredient; improved aging and wrinkle resistances | CITICORP USA, INC. | 2005-06-02 | — | — | US | disclosed |
| EP-0669323-B2 | COSMETIC AND DERMATOLOGICAL PREPARATIONS, CONTAINING PHENYLENE-1,4-BISBENZIMIDAZOLE SULFONIC ACIDS | HAARMANN & REIMER GMBH (DE) | 2004-04-07 | — | — | EP | disclosed |
| EP-0669323-B1 | COSMETIC AND DERMATOLOGICAL PREPARATIONS, CONTAINING PHENYLENE-1,4-BISBENZIMIDAZOLE SULFONIC ACIDS | HAARMANN & REIMER GMBH (DE) | 2001-05-09 | — | — | EP | disclosed |
| US-6037473-A | AS SUNSCREENS IN COSMETIC AND PHARMACEUTICAL PREPARATIONS; FOR ENHANCING PHOTOSTABILITY OF INDUSTRIAL PRODUCTS SUCH AS PAINTS, VARNISHES, PLASTICS, TEXTILES, PACKAGING MATERIALS AND RUBBERS | HAARMANN & REIMER GMBH (DE) | 2000-03-14 | — | — | US | disclosed |
| US-5961960-A | Use of substituted benzazoles as UV absorbers, new benzazoles and processes for their preparation | HAARMANN & REIMER GMBH (DE) | 1999-10-05 | — | — | US | disclosed |
| EP-0843995-A2 | Use of substituted benzazoles as UV absorbents, new benzazoles and their preparation | HAARMANN & REIMER GMBH (DE) | 1998-05-27 | — | — | EP | disclosed |
| US-5585091-A | SUNSCREEN AGENT | HAARMANN & REIMER GMBH (DE) | 1996-12-17 | — | — | US | disclosed |
| EP-0669323-A1 | Utilization of benzazols as UV-absorbers, new benzazoles and process for their preparation | HAARMANN & REIMER GMBH (DE) | 1995-08-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070020216-A1 | Compositions for Treating Keratinous Surfaces | KRT18, FN1, HKDC1 | CES1 4549/4885SRC 4181/4885TSHR 3157/4885 |
| US-20050118124-A1 | A foundation makeup, concealer, powder, eyeshadow, mascara, eyeliner, or blush with Acetyl Hexapeptide-3 as a primary ingredient; improved aging and wrinkle resistances | IGFBP3, MC3R, MC1R | CES1 4010/4885SRC 4100/4885TSHR 1186/4885 |
| US-20150065728-A1 | NOVEL BENZYLIDENE AZOLIDINE DERIVATIVE OR SALT THEREOF | IL4I1, SLC6A19, SLC9B2 | CES1 4107/4885SRC 3449/4885TSHR 3860/4885 |
| US-20070041922-A1 | Compositions for Treating Keratinous Surfaces | CUTA, KRT18, MCOLN2 | CES1 4010/4885SRC 2578/4885TSHR 2257/4885 |
| US-20100183529-A1 | Cosmetic compositions comprising photostabilized dibenzoylmethane compounds and 2-pyrrolidinone-4- carboxy esters | CYP1B1, C1S, DDT | CES1 122/4885SRC 4033/4885TSHR 3085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.