Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.52 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8467638 | 0.83 | ADORA2A (0.56) | ADORA1ADORA2AADCY1HTT | |
| SCHEMBL8466976 | 0.83 | ADORA2A (0.59) | ADORA1CYP1A2ADORA2AADCY1TSHR | |
| SCHEMBL10362340 | 0.76 | ADORA2A (0.61) | ADORA1CYP1A2CYP2D6ADORA2AADCY1 | |
| SCHEMBL8467390 | 0.75 | ADORA2A (0.88) | ADORA1ADORA2AADCY1ADORA2B | |
| SCHEMBL8467559 | 0.75 | ADORA2A (0.60) | ADORA1CYP1A2CYP2D6ADORA2AADCY1 | |
| SCHEMBL8467138 | 0.75 | ADORA2A (0.60) | ADORA1CYP1A2CYP2D6ADORA2AADCY1 | |
| SCHEMBL8464071 | 0.75 | ADORA2A (0.60) | ADORA1CYP1A2CYP2D6ADORA2AADCY1 | |
| SCHEMBL7812370 | 0.75 | ADORA2A (0.63) | ADORA1CYP1A2CYP2D6ADORA2AADCY1 | |
| SCHEMBL13531724 | 0.75 | ADORA1 (0.88) | NFKB1ADORA1PMP22CYP1A2CYP3A4 | |
| SCHEMBL8463849 | 0.74 | TLR7 (0.59) | ADORA1ADORA2AADCY1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994361-A | ANTITUMOR, ANTICANCER AGENT | BIOCHEM PHARMA (CA) | 1999-11-30 | — | — | US | claimed |