Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.56 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.55 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.53 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.53 |
| ▸ | PDE4A | P27815 | 3/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.51 |
| ▸ | PDE5A | O76074 | 2/20 | 0.50 |
| ▸ | PDE1A | P54750 | 2/20 | 0.50 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.50 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.46 |
| ▸ | AHCY | P23526 | 1/20 | 0.45 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19242632 | 0.88 | YTHDC1 (0.61) | ADORA2AYTHDC1P2RY1PDE4APDE4B | |
| SCHEMBL8466976 | 0.86 | ADORA2A (0.59) | ADORA2AADCY1ADORA1ADCY5TMIGD3 | |
| SCHEMBL8463785 | 0.83 | NFKB1 (0.53) | ADORA2AADCY1ADORA1HTT | |
| SCHEMBL10362340 | 0.80 | ADORA2A (0.61) | ADORA2AADCY1ADORA1ADCY5 | |
| SCHEMBL12179919 | 0.80 | YTHDC1 (0.61) | ADORA2AYTHDC1P2RY1PDE4APDE4B | |
| SCHEMBL8467138 | 0.78 | ADORA2A (0.60) | ADORA2AADCY1ADORA1ADCY5 | |
| SCHEMBL8467559 | 0.78 | ADORA2A (0.60) | ADORA2AADCY1ADORA1ADCY5 | |
| SCHEMBL8464071 | 0.78 | ADORA2A (0.60) | ADORA2AADCY1ADORA1ADCY5 | |
| SCHEMBL8467390 | 0.78 | ADORA2A (0.88) | ADORA2AADCY1ADORA1ADCY5AHCY | |
| SCHEMBL7812370 | 0.78 | ADORA2A (0.63) | ADORA2AADCY1ADORA1ADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994361-A | ANTITUMOR, ANTICANCER AGENT | BIOCHEM PHARMA (CA) | 1999-11-30 | — | — | US | claimed |