Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.59 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | TK1 | P04183 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10362340 | 0.79 | ADORA2A (0.61) | TLR7TLR9ADORA2AADCY1TSHR | |
| SCHEMBL8467390 | 0.77 | ADORA2A (0.88) | ADORA2AADCY1ALDH1A1ADORA1ADCY5 | |
| SCHEMBL8467559 | 0.77 | ADORA2A (0.60) | TLR7TLR9ADORA2AADCY1TSHR | |
| SCHEMBL8464071 | 0.77 | ADORA2A (0.60) | ADORA2AADCY1TSHRADORA1ADCY5 | |
| SCHEMBL8467138 | 0.77 | ADORA2A (0.60) | ADORA2AADCY1TSHRADORA1ADCY5 | |
| SCHEMBL7812370 | 0.77 | ADORA2A (0.63) | TLR7TLR9ADORA2AADCY1TSHR | |
| SCHEMBL19553487 | 0.76 | ADORA2A (0.91) | ADORA2AADCY1ADORA1ADCY5 | |
| SCHEMBL8466896 | 0.76 | ADORA2A (0.61) | ADORA2AADCY1TSHRADORA1ADCY5 | |
| SCHEMBL8467638 | 0.74 | ADORA2A (0.56) | ADORA2AADCY1ADORA1ADCY5 | |
| SCHEMBL8465881 | 0.74 | ADORA2A (0.56) | TLR7TLR9ADORA2AADCY1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994361-A | ANTITUMOR, ANTICANCER AGENT | BIOCHEM PHARMA (CA) | 1999-11-30 | — | — | US | claimed |