Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6728055 | 0.98 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL29923705 | 0.98 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL27496311 | 0.86 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL18432608 | 0.86 | KDM4E (0.44) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL13171240 | 0.86 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL28621044 | 0.86 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1MAPTPKM | |
| Hydrochloric Acid SCHEMBL7705494 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL9420603 | 0.83 | TSHR (0.57) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL18703608 | 0.83 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL8340285 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886218-A | REACTING 3,4-DICHLOROTOLUENE WITH ACETYL CHLORIDE OR CHLOROACETYL CHLORIDE USING A FRIEDEL-CRAFTS CATALYST; OXIDIZING THE ACETYLATED INTERMEDIATE IN THE PRESENCE OF AN ALKALI TO PRODUCE THE SALT SUBSEQUENTLY HYDROLYZED | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | disclosed |
| EP-0805140-A1 | Process for producing 4,5-dichloro-2-methylbenzoic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-05 | — | — | EP | disclosed |