Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29923705 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL8464010 | 0.98 | ALDH1A1 (0.46) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL13171240 | 0.88 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL18432608 | 0.88 | KDM4E (0.44) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL27496311 | 0.88 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL28621044 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1MAPTPKM | |
| Hydrochloric Acid SCHEMBL7705494 | 0.86 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL18703608 | 0.85 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL8340285 | 0.84 | ALDH1A1 (0.48) | ALDH1A1KDM4EMEN1MAPTPKM | |
| SCHEMBL10915062 | 0.83 | POLB (0.47) | ALDH1A1KDM4EMEN1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886218-A | REACTING 3,4-DICHLOROTOLUENE WITH ACETYL CHLORIDE OR CHLOROACETYL CHLORIDE USING A FRIEDEL-CRAFTS CATALYST; OXIDIZING THE ACETYLATED INTERMEDIATE IN THE PRESENCE OF AN ALKALI TO PRODUCE THE SALT SUBSEQUENTLY HYDROLYZED | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | claimed |
| EP-0805140-A1 | Process for producing 4,5-dichloro-2-methylbenzoic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-05 | — | — | EP | claimed |
| JP-10053558-A | — | — | None | — | — | JP | disclosed |
| CN-115028596-B | Method for preparing topramezone intermediate | 帕潘纳(北京)科技有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-115028596-A | Process for preparing topramezone intermediates | 帕潘纳(北京)科技有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-109970551-B | Preparation method of o-methyl aryl formic acid derivative | 华侨大学 | 2021-07-30 | — | — | CN | disclosed |
| US-9758474-B2 | Immunomodulator and anti-inflammatory compounds | INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2017-09-12 | — | — | US | disclosed |
| US-9758474-B2 | Immunomodulator and anti-inflammatory compounds | INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2017-09-12 | — | — | US | disclosed |
| US-20140220050-A1 | NOVEL IMMUNOMODULATOR AND ANTI-INFLAMMATORY COMPOUNDS | INCOZEN THERAPEUTICS PVT. LTD. (CH) | 2014-08-07 | — | — | US | disclosed |
| US-20140220050-A1 | NOVEL IMMUNOMODULATOR AND ANTI-INFLAMMATORY COMPOUNDS | INCOZEN THERAPEUTICS PVT. LTD. (CH) | 2014-08-07 | — | — | US | disclosed |
| US-20120238750-A1 | AROMATIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. | 2012-09-20 | — | — | US | disclosed |
| US-5886218-A | REACTING 3,4-DICHLOROTOLUENE WITH ACETYL CHLORIDE OR CHLOROACETYL CHLORIDE USING A FRIEDEL-CRAFTS CATALYST; OXIDIZING THE ACETYLATED INTERMEDIATE IN THE PRESENCE OF AN ALKALI TO PRODUCE THE SALT SUBSEQUENTLY HYDROLYZED | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | disclosed |
| US-5886218-A | REACTING 3,4-DICHLOROTOLUENE WITH ACETYL CHLORIDE OR CHLOROACETYL CHLORIDE USING A FRIEDEL-CRAFTS CATALYST; OXIDIZING THE ACETYLATED INTERMEDIATE IN THE PRESENCE OF AN ALKALI TO PRODUCE THE SALT SUBSEQUENTLY HYDROLYZED | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | disclosed |
| US-5767289-A | HERBICIDE INTERMEDIATES | IDEMITSU KOSAN COMPANY, LIMITED (JP) | 1998-06-16 | — | — | US | disclosed |
| JP-H1053558-A | PRODUCTION OF 4,5-DICHLORO-2-METHYLBENZOIC ACID | HOECHST AG | 1998-02-24 | — | — | JP | disclosed |
| EP-0810226-A1 | PYRAZOLE DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |
| EP-0805140-A1 | Process for producing 4,5-dichloro-2-methylbenzoic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0805140-A1 | Process for producing 4,5-dichloro-2-methylbenzoic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0805140-A1 | Process for producing 4,5-dichloro-2-methylbenzoic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-05 | — | — | EP | disclosed |
| US-5607898-A | HERBICIDES | IDEMITSU KOSAN COMPANY, LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238750-A1 | AROMATIC COMPOUND | CBR1, CBR3, CYP1A1 | ALDH1A1 565/4885KDM4E 1219/4885MEN1 1020/4885 |
| US-20140220050-A1 | NOVEL IMMUNOMODULATOR AND ANTI-INFLAMMATORY COMPOUNDS | DHODH, DLD, DHFR | ALDH1A1 109/4885KDM4E 1861/4885MEN1 4837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.