Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 2/20 | 0.42 |
| ▸ | DNA2 | P51530 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | DTYMK | P23919 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30399151 | 0.85 | CDK2 (0.55) | CDK2TSHRALDH1A1APEX1TDP1 | |
| SCHEMBL772810 | 0.85 | CDK2 (0.55) | CDK2TSHRALDH1A1APEX1TDP1 | |
| SCHEMBL9455556 | 0.81 | TSHR (0.57) | CDK2TSHRALDH1A1APEX1TDP1 | |
| SCHEMBL8462678 | 0.78 | GRIN2D (0.68) | ALDH1A1POLBCASP6GRIN2DGRIN2A | |
| SCHEMBL8462734 | 0.78 | GRIN2D (0.46) | ALDH1A1POLBGRIN2DGRIN2AGRIN2B | |
| SCHEMBL8463551 | 0.78 | CDK2 (0.48) | CDK2TSHRALDH1A1APEX1TDP1 | |
| SCHEMBL27400046 | 0.77 | ALDH1A1 (0.49) | CDK2TSHRALDH1A1APEX1TDP1 | |
| SCHEMBL8463162 | 0.77 | GRIN2D (0.45) | TSHRALDH1A1POLBGRIN2DGRIN2A | |
| SCHEMBL8464339 | 0.77 | GRIN2D (0.45) | ALDH1A1POLBGRIN2DGRIN2AGRIN2B | |
| SCHEMBL8464770 | 0.77 | GRIN2D (0.45) | ALDH1A1POLBGRIN2DGRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |