⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8463898 | 0.85 | — | — | |
| SCHEMBL8461199 | 0.79 | KDM4E (0.30) | — | |
| SCHEMBL4613303 | 0.79 | HPGD (0.34) | — | |
| SCHEMBL10586948 | 0.78 | — | — | |
| SCHEMBL10493375 | 0.77 | — | — | |
| SCHEMBL10493340 | 0.77 | NPC1 (0.33) | — | |
| SCHEMBL8461481 | 0.77 | LMNA (0.33) | — | |
| SCHEMBL8463059 | 0.75 | CA2 (0.40) | — | |
| SCHEMBL8545516 | 0.74 | — | — | |
| SCHEMBL8464826 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641832-B1 | Diorganopolysiloxane-Rigid aromatic polymer compositions and preparation thereof | DOW CORNING ASIA LTD (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0641831-B1 | Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same | DOW CORNING ASIA LTD (JP) | 1997-11-12 | — | — | EP | disclosed |
| US-5527862-A | COMPATIBLE BLENDS; REINFORCED CURED COMPOSITES; HIGH STRENGTH | DOW CORNING ASIA, LTD. (JP) | 1996-06-18 | — | — | US | disclosed |
| US-5464922-A | Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same | DOW CORNING ASIA LTD. (JP) | 1995-11-07 | — | — | US | disclosed |
| EP-0641832-A1 | Diorganopolysiloxane-Rigid aromatic polymer compositions and preparation thereof | DOW CORNING ASIA, Ltd. (JP) | 1995-03-08 | — | — | EP | disclosed |
| EP-0641831-A1 | Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same | DOW CORNING ASIA, Ltd. (JP) | 1995-03-08 | — | — | EP | disclosed |