Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11789835 | 0.97 | — | — | |
| SCHEMBL11150501 | 0.92 | — | — | |
| SCHEMBL28089597 | 0.89 | CYP1A2 (0.35) | CES2CES1HSD11B1ALDH1A1NAAA | |
| SCHEMBL4836929 | 0.89 | — | — | |
| SCHEMBL4488617 | 0.80 | NAAA (0.36) | CES2CES1HSD11B1ALDH1A1NAAA | |
| SCHEMBL30835525 | 0.77 | NAAA (0.42) | NAAAEPHX2CYP1A2EPHX1 | |
| SCHEMBL3605682 | 0.76 | CES2 (0.39) | CES2CES1ALDH1A1MGLLHDAC8 | |
| SCHEMBL30835526 | 0.75 | NAAA (0.44) | NAAAEPHX2CYP1A2EPHX1L3MBTL1 | |
| SCHEMBL23547192 | 0.74 | CES2 (0.38) | CES2CES1ALDH1A1MGLLHDAC8 | |
| SCHEMBL11210860 | 0.74 | CES2 (0.38) | CES2CES1ALDH1A1MGLLHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4614816-A | Preparation of carboxylic acids and esters thereof | BP CHEMICALS LIMITED (GB) | 1986-09-30 | — | — | US | claimed |
| US-20230241597-A1 | PLATFORM FOR THE RECOVERY OF TRANSITION METAL CATALYSTS | TEXAS TECH UNIVERSITY SYSTEM | 2023-08-03 | — | — | US | disclosed |
| WO-2023072794-A1 | PIPERAZINYLSULFONYLARYL COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-05-04 | — | — | WO | disclosed |
| WO-2023061617-A1 | SULFONYLPIPERAZINYL COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-04-20 | — | — | WO | disclosed |
| WO-2020061112-A1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | METACRINE, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
| WO-2017133657-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017133670-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |
| EP-2731989-B1 | HETEROPHASIC POLYPROPYLENE WITH LOW CLTE AND HIGH STIFFNESS | BOREALIS AG (AT) | 2015-06-17 | — | — | EP | disclosed |
| EP-2731989-A1 | HETEROPHASIC POLYPROPYLENE WITH LOW CLTE AND HIGH STIFFNESS | Borealis AG (AT) | 2014-05-21 | — | — | EP | disclosed |
| WO-2013010877-A1 | HETEROPHASIC POLYPROPYLENE WITH LOW CLTE AND HIGH STIFFNESS | BOREALIS AG (AT) | 2013-01-24 | — | — | WO | disclosed |
| EP-0106656-B1 | PREPARATION OF CARBOXYLIC ACIDS AND ESTERS THEREOF | BP Chemicals Limited (GB) | 1986-09-17 | — | — | EP | disclosed |
| US-4558153-A | Preparation of carboxylic acids and esters | BP CHEMICALS LIMITED (GB) | 1985-12-10 | — | — | US | disclosed |
| EP-0096974-B1 | PROCESS FOR THE PRODUCTION OF ONE OR MORE CARBOXYLIC ACID ANHYDRIDES | BP Chemicals Limited (GB) | 1985-09-11 | — | — | EP | disclosed |
| EP-0140673-A2 | Preparation of carboxylic acids and esters | BP Chemicals Limited (GB) | 1985-05-08 | — | — | EP | disclosed |
| EP-0106656-A1 | Preparation of carboxylic acids and esters thereof | BP Chemicals Limited (GB) | 1984-04-25 | — | — | EP | disclosed |
| EP-0096974-A1 | Process for the production of one or more carboxylic acid anhydrides | BP Chemicals Limited (GB) | 1983-12-28 | — | — | EP | disclosed |
| US-4405757-A | Macromolecular complexes of amidocarbonylic water-soluble polymers and square planar platinous and equivalent organometallics | HOWELL BOBBY A | 1983-09-20 | — | — | US | disclosed |
| US-4132734-A | REACTION OF AN ETHYLENICALLY UNSATURATED COMPOUND, CARBON MONOXIDE AND H2O IN THE PRESENCE OF A COMPOUND OF RH OR IR, A HALOGEN PROMOTER AND A COMPOUND OF FG, MN, OR COBALT | MONSANTO COMPANY (US) | 1979-01-02 | — | — | US | disclosed |
| US-4000170-A | FROM OLEFINS, CARBON MONOXIDE AND H2 | MONSANTO COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
| US-3989751-A | COBALT OR NICKEL CATALYST | MONSANTO COMPANY (US) | 1976-11-02 | — | — | US | disclosed |