Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8463501 | 0.91 | AKR1B1 (0.36) | AKR1B1MAPTALOX15SMN1; SMN2HPGD | |
| SCHEMBL19678481 | 0.77 | TPMT (0.40) | AKR1B1TTRGPR17MAPTALOX15 | |
| SCHEMBL30502430 | 0.77 | TPMT (0.40) | AKR1B1TTRGPR17MAPTALOX15 | |
| SCHEMBL8464252 | 0.76 | TPMT (0.33) | AKR1B1MEN1KMT2A | |
| SCHEMBL699224 | 0.76 | TTR (0.50) | AKR1B1TTRMAPTSMN1; SMN2ITGB3 | |
| SCHEMBL8461130 | 0.75 | AKR1B1 (0.46) | AKR1B1TTRMAPTTHRBHPGD | |
| SCHEMBL8464341 | 0.73 | POLB (0.50) | AKR1B1MAPTHPGDTSHRMEN1 | |
| SCHEMBL8463313 | 0.72 | MAOB (0.41) | TTRGPR17ALOX15 | |
| SCHEMBL8459629 | 0.72 | HPGD (0.44) | AKR1B1MAPTALOX15SMN1; SMN2HPGD | |
| SCHEMBL8462903 | 0.72 | AKR1B1 (0.36) | AKR1B1MAPTALOX15THRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |