Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464249 | 0.91 | AKR1B1 (0.33) | AKR1B1ALOX15MEN1KMT2AHPGD | |
| SCHEMBL8464341 | 0.82 | POLB (0.50) | AKR1B1MEN1KMT2AHPGDTSHR | |
| SCHEMBL8459629 | 0.80 | HPGD (0.44) | AKR1B1ALOX15MEN1KMT2AHPGD | |
| SCHEMBL8464321 | 0.80 | KEAP1 (0.40) | AKR1B1HPGDMAPTHSD17B10CXCL8 | |
| SCHEMBL8462903 | 0.80 | AKR1B1 (0.36) | AKR1B1ALOX15MEN1KMT2APOLB | |
| SCHEMBL8460359 | 0.80 | TSHR (0.40) | AKR1B1MEN1KMT2ATSHRPOLB | |
| SCHEMBL8460216 | 0.77 | POLB (0.42) | AKR1B1ALOX15MEN1KMT2AHPGD | |
| SCHEMBL8461331 | 0.77 | AKR1B1 (0.32) | AKR1B1HPGDTSHRPOLBMAPT | |
| SCHEMBL8464252 | 0.77 | TPMT (0.33) | AKR1B1MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL8461777 | 0.76 | PTGS1 (0.57) | AKR1B1MEN1KMT2ATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |