Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8461438 | 0.79 | KMT2A (0.38) | POLB | |
| SCHEMBL8463313 | 0.75 | MAOB (0.41) | TTR | |
| SCHEMBL8464355 | 0.74 | POLB (0.35) | POLBNLRP3TTR | |
| SCHEMBL8462798 | 0.72 | CYP3A4 (0.37) | POLB | |
| SCHEMBL8463923 | 0.72 | KDM4E (0.36) | — | |
| SCHEMBL8460365 | 0.71 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL8464049 | 0.71 | AKR1C4 (0.36) | POLB | |
| SCHEMBL8463965 | 0.71 | CES2 (0.38) | — | |
| SCHEMBL8464421 | 0.68 | POLB (0.37) | POLB | |
| SCHEMBL8464430 | 0.67 | CES2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |