Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8461438 | 0.83 | KMT2A (0.38) | POLBSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL8464336 | 0.79 | ALDH1A1 (0.44) | SMN1; SMN2MAPK1ALDH1A1HPGDTSHR | |
| SCHEMBL8464286 | 0.77 | HTT (0.44) | ALDH1A1KMT2AMEN1HTTMAPT | |
| SCHEMBL8464905 | 0.77 | ALDH1A1 (0.45) | POLBALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL8463309 | 0.76 | SMN1; SMN2 (0.41) | POLBSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL8460620 | 0.76 | MTNR1A (0.33) | POLBSMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL8460617 | 0.76 | KCNK3 (0.45) | MAPK1ALDH1A1NPC1 | |
| Phosphoric Acid SCHEMBL8464864 | 0.74 | THRB (0.42) | POLBSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL8463044 | 0.74 | POLB (0.36) | POLBSMN1; SMN2MAPK1ALDH1A1KMT2A | |
| SCHEMBL27452471 | 0.72 | MAPK1 (0.36) | POLBSMN1; SMN2MAPK1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |