Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8463268 | 0.90 | KDM4E (0.50) | KDM4ECSNK2A1METAP2TPMTALDH1A1 | |
| SCHEMBL8464696 | 0.82 | TPMT (0.43) | KDM4ETPMTALDH1A1NOTUMMYC | |
| SCHEMBL2565865 | 0.78 | SMN1; SMN2 (0.42) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL8463923 | 0.77 | KDM4E (0.36) | KDM4EMETAP2ALDH1A1GAALMNA | |
| SCHEMBL11770168 | 0.74 | KDM4E (0.63) | KDM4ECSNK2A1METAP2TPMTALDH1A1 | |
| SCHEMBL1259082 | 0.74 | KDM4E (0.63) | KDM4ECSNK2A1METAP2TPMTALDH1A1 | |
| SCHEMBL8460219 | 0.73 | KDM4E (0.38) | KDM4EALDH1A1NOTUMGAALMNA | |
| SCHEMBL8464329 | 0.73 | CYP3A4 (0.40) | KDM4EALDH1A1NOTUMGAALMNA | |
| SCHEMBL8461351 | 0.73 | KDM4E (0.39) | KDM4EALDH1A1NOTUMGAALMNA | |
| SCHEMBL6915536 | 0.72 | KDM4E (0.61) | KDM4ECSNK2A1METAP2TPMTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |