Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | TPMT | P51580 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464513 | 0.90 | KDM4E (0.55) | KDM4ECSNK2A1TPMTMYCTTR | |
| SCHEMBL8460400 | 0.79 | CA1 (0.46) | KDM4EMYCHCAR1ALDH1A1KMT2A | |
| SCHEMBL8464742 | 0.78 | AKR1C3 (0.42) | — | |
| SCHEMBL8464012 | 0.77 | AKR1C3 (0.52) | KDM4EMYCKMT2AMEN1GPR35 | |
| SCHEMBL8461449 | 0.77 | AKR1C4 (0.52) | KDM4ETPMTMYCNOTUMHCAR1 | |
| SCHEMBL8460863 | 0.77 | PTPRC (0.39) | KDM4ETPMTALDH1A1KMT2AMEN1 | |
| SCHEMBL8462420 | 0.77 | KEAP1 (0.45) | KDM4ETTRNOTUMHCAR1ALDH1A1 | |
| SCHEMBL8462433 | 0.77 | SMN1; SMN2 (0.47) | KDM4EALDH1A1KMT2ARXRAMEN1 | |
| SCHEMBL3392534 | 0.75 | KDM4E (0.58) | KDM4ECSNK2A1TPMTMYCTTR | |
| SCHEMBL8464696 | 0.75 | TPMT (0.43) | KDM4ETPMTMYCTTRNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |