Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464663 | 1.00 | LTA4H (0.35) | LTA4HFDPSHDAC1HDAC6ITGB3 | |
| SCHEMBL8466911 | 0.85 | ADCY5 (0.37) | HDAC1ITGB3ITGA2BITGAVALDH1A1 | |
| SCHEMBL8465859 | 0.85 | ADCY5 (0.47) | ALDH1A1EP300 | |
| SCHEMBL8466600 | 0.85 | ADCY5 (0.47) | ALDH1A1EP300 | |
| SCHEMBL8467714 | 0.84 | ADCY5 (0.36) | HDAC1ITGB3ITGA2BITGAVALDH1A1 | |
| SCHEMBL8466905 | 0.84 | ADCY5 (0.36) | FDPSHDAC6ITGB3ITGA2B | |
| SCHEMBL8467662 | 0.84 | ADCY5 (0.36) | HDAC1ITGB3ITGA2BALDH1A1 | |
| SCHEMBL8465925 | 0.84 | ADCY5 (0.36) | HDAC1ITGB3ITGA2BALDH1A1 | |
| SCHEMBL8464251 | 0.84 | ADCY5 (0.36) | FDPSHDAC6ITGB3ITGA2B | |
| SCHEMBL8467074 | 0.84 | P2RY1 (0.43) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994361-A | ANTITUMOR, ANTICANCER AGENT | BIOCHEM PHARMA (CA) | 1999-11-30 | — | — | US | claimed |