Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL912509 | 0.76 | ESR1 (0.33) | MAPTESR1ESR2 | |
| SCHEMBL335769 | 0.76 | TSHR (0.35) | MAPTESR1ESR2 | |
| SCHEMBL21723560 | 0.74 | ESR1 (0.32) | MAPTESR1ESR2 | |
| Iodide SCHEMBL8897376 | 0.73 | ESR1 (0.33) | ESR1ESR2 | |
| SCHEMBL21061710 | 0.73 | MAPT (0.33) | MAPTESR1ESR2 | |
| SCHEMBL2971870 | 0.73 | MAPT (0.37) | MAPTESR1ESR2 | |
| SCHEMBL19741576 | 0.72 | ESR1 (0.39) | MAPTESR1ESR2 | |
| SCHEMBL2048191 | 0.72 | ESR1 (0.39) | MAPTESR1ESR2 | |
| SCHEMBL13621322 | 0.72 | ESR1 (0.39) | MAPTESR1ESR2 | |
| SCHEMBL17816335 | 0.71 | ESR1 (0.35) | MAPTESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933406-A | OXYGEN-PERMEABLE, RIGID | NIPPON OIL AND FATS CO., LTD. (JP) | 1990-06-12 | — | — | US | claimed |
| US-5883152-A | HARD CONTACT LENS CONSISTING OF A COPOLYMER OF CARBOXYLIC ACID ESTER MONOMER, TRIS(TRIMETHYLSILOXY)SILYLPROPYL(METH)ACRYLATE, AND COPOLYMERIZABLE MONOMER | NIPPON OIL AND FATS CO., LTD. (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0425831-B1 | Contact lens | NIPPON OILS & FATS CO LTD (JP) | 1995-05-03 | — | — | EP | disclosed |
| EP-0425831-A2 | Contact lens | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1991-05-08 | — | — | EP | disclosed |
| US-4933406-A | OXYGEN-PERMEABLE, RIGID | NIPPON OIL AND FATS CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |