Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464438 | 0.80 | LMNA (0.56) | PTPN11ALDH1A1S1PR3TSHRPTPN1 | |
| SCHEMBL9067305 | 0.79 | PTPN11 (0.68) | PLA2G2APTPN11ALDH1A1HPGDTP53 | |
| SCHEMBL27494596 | 0.79 | PTPN11 (0.68) | PLA2G2APTPN11ALDH1A1HPGDTP53 | |
| SCHEMBL8460897 | 0.78 | PLA2G2A (0.55) | PLA2G2APTPN11ALDH1A1HPGDS1PR3 | |
| SCHEMBL1200763 | 0.78 | PLA2G2A (0.66) | PLA2G2APTPN11ALDH1A1HPGDTP53 | |
| SCHEMBL6023328 | 0.78 | PLA2G2A (0.66) | PLA2G2APTPN11ALDH1A1HPGDTP53 | |
| SCHEMBL1108059 | 0.78 | PLA2G2A (0.66) | PLA2G2APTPN11ALDH1A1HPGDTP53 | |
| SCHEMBL318045 | 0.78 | PLA2G2A (0.66) | PLA2G2APTPN11ALDH1A1HPGDTP53 | |
| SCHEMBL1200906 | 0.78 | PLA2G2A (0.66) | PLA2G2APTPN11ALDH1A1HPGDTP53 | |
| SCHEMBL1201538 | 0.78 | PLA2G2A (0.66) | PLA2G2APTPN11ALDH1A1HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |