Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8463375 | 0.85 | AKR1C3 (0.36) | AKR1C3AKR1C4AKR1C2AKR1C1GPR35 | |
| SCHEMBL8462915 | 0.81 | AKR1C3 (0.36) | AKR1C3AKR1C4AKR1C2AKR1C1GPR35 | |
| SCHEMBL8941154 | 0.78 | AKR1C4 (0.42) | AKR1C3AKR1C4AKR1C2AKR1C1GPR35 | |
| SCHEMBL8464012 | 0.74 | AKR1C3 (0.52) | AKR1C3AKR1C4AKR1C2AKR1C1GPR35 | |
| SCHEMBL8462622 | 0.73 | AKR1C3 (0.57) | AKR1C3AKR1C4AKR1C2AKR1C1GPR35 | |
| SCHEMBL28018954 | 0.73 | TTR (0.42) | AKR1C3AKR1C4AKR1C2AKR1C1LCK | |
| SCHEMBL8461176 | 0.72 | TTR (0.50) | AKR1C3AKR1C4AKR1C2AKR1C1LCK | |
| SCHEMBL3664560 | 0.71 | AKR1C3 (0.43) | AKR1C3AKR1C4AKR1C2AKR1C1GPR35 | |
| SCHEMBL8462670 | 0.70 | AKR1C3 (0.36) | AKR1C3AKR1C4AKR1C2AKR1C1GPR35 | |
| SCHEMBL8464782 | 0.70 | HSD17B10 (0.38) | AKR1C3AKR1C4AKR1C2AKR1C1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |