Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8463328 | 0.76 | GRIN2D (0.38) | HSD17B10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8461798 | 0.73 | HSD17B10 (0.38) | HSD17B10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8464814 | 0.73 | KDM4E (0.41) | HSD17B10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8460628 | 0.73 | TSHR (0.49) | HSD17B10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL28245208 | 0.72 | ALDH1A1 (0.41) | HSD17B10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL955263 | 0.71 | HSD17B10 (0.64) | HSD17B10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29680388 | 0.71 | HSD17B10 (0.64) | HSD17B10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8464339 | 0.71 | GRIN2D (0.45) | HSD17B10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8464929 | 0.70 | AKR1C3 (0.36) | HSD17B10KDM4EGPR35PRNPPTPN1 | |
| SCHEMBL6915050 | 0.70 | HSD17B10 (0.62) | HSD17B10MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |