Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.52 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8462622 | 0.90 | AKR1C3 (0.57) | AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10 | |
| SCHEMBL8460400 | 0.79 | CA1 (0.46) | HSD17B10KDM4EMYCMEN1KMT2A | |
| SCHEMBL8463268 | 0.77 | KDM4E (0.50) | KDM4EMYCGPR35MEN1KMT2A | |
| SCHEMBL8461449 | 0.77 | AKR1C4 (0.52) | AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10 | |
| SCHEMBL8462420 | 0.77 | KEAP1 (0.45) | AKR1C2AKR1C1HSD17B10KDM4EMEN1 | |
| SCHEMBL8460863 | 0.77 | PTPRC (0.39) | HSD17B10KDM4EMEN1KMT2ARXFP1 | |
| SCHEMBL6437956 | 0.75 | AKR1C3 (0.60) | AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10 | |
| SCHEMBL8461176 | 0.75 | TTR (0.50) | AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10 | |
| SCHEMBL8464742 | 0.74 | AKR1C3 (0.42) | AKR1C3AKR1C2AKR1C1AKR1C4CA5A | |
| SCHEMBL8464929 | 0.74 | AKR1C3 (0.36) | AKR1C3AKR1C2AKR1C1AKR1C4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |