Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.74 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.74 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8465432 | 1.00 | HSP90AA1 (0.74) | HSP90AA1HSP90AB1ELANENPC1ALDH1A1 | |
| SCHEMBL8465304 | 0.89 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1 | |
| SCHEMBL8465085 | 0.89 | HSP90AA1 (0.57) | HSP90AA1HSP90AB1 | |
| SCHEMBL1274825 | 0.85 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL8467084 | 0.84 | HSP90AA1 (0.74) | HSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL8464975 | 0.84 | HSP90AA1 (0.74) | HSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL8464925 | 0.77 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1NPC1ALDH1A1RAB9A | |
| SCHEMBL8464963 | 0.76 | HSP90AA1 (0.69) | HSP90AA1HSP90AB1 | |
| SCHEMBL8465103 | 0.76 | HSP90AA1 (0.69) | HSP90AA1HSP90AB1 | |
| SCHEMBL8465216 | 0.75 | HSP90AA1 (0.79) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981544-A | Mono-- or diketone tetracyclic derivatives and therapeutical uses thereof | LABORATOIRE INNOTHERA (FR) | 1999-11-09 | — | — | US | claimed |
| US-5981544-A | Mono-- or diketone tetracyclic derivatives and therapeutical uses thereof | LABORATOIRE INNOTHERA (FR) | 1999-11-09 | — | — | US | disclosed |