Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8467410 | 0.85 | HTR2A (0.39) | HTR2AHRH1ALDH1A1TSHRHRH3 | |
| SCHEMBL3226604 | 0.72 | ALDH1A1 (0.40) | ALDH1A1TSHRCYP1A2 | |
| SCHEMBL7648197 | 0.72 | ALDH1A1 (0.40) | ALDH1A1TSHRCYP1A2 | |
| SCHEMBL8465157 | 0.71 | HTR2A (0.37) | HTR2AHRH1 | |
| SCHEMBL13049890 | 0.67 | LMNA (0.36) | ALDH1A1TSHRCYP2D6SMN1; SMN2 | |
| SCHEMBL3220532 | 0.66 | ALDH1A1 (0.34) | ALDH1A1TSHR | |
| SCHEMBL4197779 | 0.66 | ALDH1A1 (0.34) | ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL32685440 | 0.66 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL8164102 | 0.64 | — | — | |
| SCHEMBL21216 | 0.62 | ALDH1A1 (0.91) | ALDH1A1TSHRDNM1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5986029-A | POLYMERIZATION CATALYSTS FOR OLEFINS USING TRANSITION METAL COMPLEXES AND COCATALYST | DSM N.V. (NL) | 1999-11-16 | — | — | US | disclosed |
| CN-1171794-A | Catalyst composition and process for olefin polymerization | DSM NV (NL) | 1998-01-28 | — | — | CN | disclosed |
| EP-0789718-A1 | CATALYST COMPOSITION AND PROCESS FOR THE POLYMERIZATION OF AN OLEFIN | DSM N.V. (NL) | 1997-08-20 | — | — | EP | disclosed |
| WO-1996013529-A1 | CATALYST COMPOSITION AND PROCESS FOR THE POLYMERIZATION OF AN OLEFIN | DSM N.V. (NL) | 1996-05-09 | — | — | WO | disclosed |