Phenol

Phenol

SCHEMBL8465261

CC(C)CCCCCCc1ccc(O)c(CCCCCCC(C)C)c1.Oc1ccccc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
IGF1R P08069 3/20 0.46
ALOX15 P16050 3/20 0.46
OPRM1 P35372 3/20 0.43
OPRD1 P41143 3/20 0.43
OPRK1 P41145 3/20 0.43
GABRA1 P14867 1/20 0.43
GABRB2 P47870 1/20 0.43
GRIN2D O15399 1/20 0.41
GRIN2A Q12879 1/20 0.41
GRIN2B Q13224 1/20 0.41
GRIN2C Q14957 1/20 0.41
TRPV1 Q8NER1 2/20 0.41
BCHE P06276 1/20 0.40
KAT8 Q9H7Z6 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8465007 0.91 GABRA1 (0.50) IGF1RALOX15GABRA1GABRB2GRIN2D
SCHEMBL8461732 0.91 GABRA1 (0.50) IGF1RALOX15GABRA1GABRB2GRIN2D
SCHEMBL27708224 0.86 KAT8 (0.48) IGF1RALOX15GABRA1GABRB2KAT8
SCHEMBL8204385 0.85 GABRA1 (0.53) IGF1RALOX15OPRK1GABRA1GABRB2
Phenol SCHEMBL11244924 0.84 MGLL (0.46) ALOX15OPRM1OPRD1OPRK1KAT8
SCHEMBL11600670 0.84 GABRA1 (0.49) IGF1RALOX15GABRA1GABRB2GRIN2D
SCHEMBL9504205 0.83 KAT8 (0.51) ALOX15GABRA1GABRB2KAT8
SCHEMBL9502998 0.83 KAT8 (0.51) ALOX15GABRA1GABRB2KAT8
SCHEMBL9502141 0.82 GABRA1 (0.47) IGF1RALOX15OPRK1GABRA1GABRB2
SCHEMBL10783247 0.81 TYR (0.49) IGF1RALOX15GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0548906-B1 Method for preparing nuclear-substituted salicylic acid metal salts and color developer for pressure-sensitive recording sheets SANKO KAIHATSU KAGAKU KENK (JP) 1999-03-31 EP claimed