Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.49 |
| ▸ | CES1 | P23141 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 6/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.43 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.42 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.42 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.42 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6419873 | 0.87 | GAA (0.56) | CES2CES1KAT6AATMNPC1 | |
| SCHEMBL15757732 | 0.86 | CES2 (0.47) | CES2CES1CNR2ATMNPC1 | |
| Ammonia Solution, Strong SCHEMBL28774251 | 0.86 | GAA (0.59) | CES2CES1KAT6AATMNPC1 | |
| SCHEMBL6416530 | 0.83 | CES2 (0.55) | CES2CES1BCHEKAT6ANPC1 | |
| SCHEMBL2886082 | 0.82 | KMT2A (0.49) | CES2CES1CNR2GUCY1B2GUCY1A2 | |
| SCHEMBL17968653 | 0.79 | ATM (0.44) | CNR2ATMNPC1RAB9AKMT2A | |
| SCHEMBL6421818 | 0.76 | KMT2A (0.44) | CES2CES1CNR2GUCY1B2GUCY1A2 | |
| SCHEMBL6415236 | 0.76 | POLB (0.50) | CNR2ATMNPC1RAB9ACNR1 | |
| SCHEMBL6419694 | 0.75 | CNR2 (0.54) | CES2CES1CNR2ATMNPC1 | |
| SCHEMBL6419790 | 0.75 | CNR2 (0.51) | CES2CES1CNR2ATMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888347-A1 | PHARMACEUTICALLY USEFUL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034893-A1 | PHARMACEUTICALLY USEFUL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-09-25 | — | — | WO | disclosed |