Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1201261 | 0.85 | CYP2A6 (0.33) | DRD2 | |
| SCHEMBL818182 | 0.83 | JAK2 (0.33) | ENPP1JAK2DRD2KIF11 | |
| SCHEMBL6056248 | 0.80 | — | — | |
| SCHEMBL8465425 | 0.79 | ENPP1 (0.33) | ENPP1JAK2DRD2KIF11 | |
| SCHEMBL2524021 | 0.78 | ENPP1 (0.36) | ENPP1JAK2BACE1DRD2KIF11 | |
| Chloromethane SCHEMBL8465733 | 0.77 | ENPP1 (0.32) | ENPP1JAK2DRD2KIF11 | |
| SCHEMBL8462246 | 0.76 | ENPP1 (0.31) | ENPP1JAK2BACE1DRD2KIF11 | |
| SCHEMBL6056149 | 0.76 | USP30 (0.32) | DRD2 | |
| SCHEMBL27687634 | 0.76 | KIF11 (0.36) | ENPP1JAK2BACE1DRD2KIF11 | |
| SCHEMBL4556848 | 0.75 | KIF11 (0.33) | ENPP1JAK2BACE1DRD2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859272-A | METALLOCENES; PRODUCES POLYOLEFINS HAVING A HIGH MELTING POINT AND A HIGH MOLECULAR WEIGHT; HIGH POLYMERIZATION ACTIVITY | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| US-5616663-A | TRANSITION METAL COMPOUND, ALUMINOXANE, COMPOUND WHICH REACTS WITH TRANSITION METAL COMPOUND TO FORM ION PAIR | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-01 | — | — | US | disclosed |