SCHEMBL8465340

SCHEMBL8465340

CCC1=Cc2c(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)cccc2C1[Zr](Cl)(Cl)(C1C(CC)=Cc2c(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)cccc21)=[Si](C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.33
HTR7 P34969 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8465874 0.90 DRD2 (0.34)
SCHEMBL8461187 0.87
SCHEMBL8169998 0.86 HTR1A (0.34) HTR1AHTR7
SCHEMBL8464437 0.86 HTR1A (0.34) HTR1AHTR7
SCHEMBL5951126 0.84 HTR1A (0.33) HTR1AHTR7
SCHEMBL6377741 0.84 HTR1A (0.33) HTR1AHTR7
SCHEMBL5952972 0.84 HTR1A (0.33) HTR1AHTR7
SCHEMBL8464914 0.84 EDNRB (0.34)
SCHEMBL1238168 0.84 HTR1A (0.30) HTR1AHTR7
SCHEMBL8465696 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5859272-A METALLOCENES; PRODUCES POLYOLEFINS HAVING A HIGH MELTING POINT AND A HIGH MOLECULAR WEIGHT; HIGH POLYMERIZATION ACTIVITY MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1999-01-12 US disclosed
US-5616663-A TRANSITION METAL COMPOUND, ALUMINOXANE, COMPOUND WHICH REACTS WITH TRANSITION METAL COMPOUND TO FORM ION PAIR MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-04-01 US disclosed