Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28976377 | 0.77 | ALOX15 (0.37) | ALOX15MAPK1MAPTEP300HIF1A | |
| SCHEMBL28976380 | 0.77 | ALOX15 (0.37) | ALOX15MAPK1MAPTEP300HIF1A | |
| SCHEMBL8089814 | 0.77 | MAPK1 (0.37) | ALOX15MAPK1MAPTCYP2C19EP300 | |
| SCHEMBL8098921 | 0.77 | MAPK1 (0.37) | ALOX15MAPK1MAPTCYP2C19EP300 | |
| SCHEMBL27519971 | 0.77 | ALOX15 (0.37) | ALOX15MAPK1MAPTEP300HIF1A | |
| SCHEMBL867536 | 0.77 | NPSR1 (0.35) | MAPK1CYP2C19ACHE | |
| Hydrochloric Acid SCHEMBL29069900 | 0.76 | MAPK1 (0.36) | ALOX15MAPK1MAPTEP300HIF1A | |
| SCHEMBL11583591 | 0.74 | ALOX15 (0.36) | ALOX15MAPK1EP300HIF1ACREBBP | |
| SCHEMBL27651835 | 0.74 | HSD11B1 (0.36) | CYP19A1EP300HIF1ACREBBPHSD11B1 | |
| SCHEMBL998437 | 0.72 | ALOX15 (0.39) | ALOX15MAPK1EP300HIF1ACREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766660-B1 | CYCLOHEXANONE DERIVATIVES, METHOD OF PREPARING THEM AND INTERMEDIATES USED IN THE METHOD | SCHERING AG (DE) | 1999-12-29 | — | — | EP | claimed |