SCHEMBL81413

SCHEMBL81413

C=CC(=O)OCCCC(C)(C)O[SiH3]

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.55
ALDH1A1 P00352 4/20 0.55
CYP3A4 P08684 2/20 0.55
HPGD P15428 1/20 0.55
TP53 P04637 3/20 0.46
HIF1A Q16665 3/20 0.46
HSD17B10 Q99714 1/20 0.46
THRB P10828 2/20 0.42
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ATM Q13315 1/20 0.36
HCAR2 Q8TDS4 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL441050 0.97 TSHR (0.60) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16286690 0.95 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16286807 0.95 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL108963 0.89 TSHR (0.48) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL5070573 0.86 TSHR (0.42) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL7569324 0.86 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL8965481 0.84 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL21081906 0.84 TSHR (0.43) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL22926219 0.83 TSHR (0.60) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL5160299 0.82 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1097 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629657-B2 Lithium ion adsorbents EMPOWER INNOVATION & TECHNOLOGY LLC (US) 2026-05-19 US claimed
EP-4326795-B1 POLYMERIZATION OF A SILANE-MODIFIED POLYMER, WHICH IS PRODUCED BY MEANS OF A RADICAL CHAIN POLYMERIZATION, IN A POLYOL OR IN A PREPOLYMER WITH TERMINAL ISOCYANATE GROUPS, AND USE THEREOF IN POLYURETHANE FORMULATIONS FOLLMANN GMBH & CO KG (DE) 2026-02-25 EP claimed
US-12469872-B2 Fluoropolymer hybrid composite SYENSQO SA (BE) 2025-11-11 US claimed
EP-4605483-A1 FREE-RADICAL POLYMERISATION OF UV-CROSSLINKING SILANE ACRYLATES IN AN ISOCYANATE-CONTAINING POLYURETHANE MATRIX Follmann GmbH & Co. KG (DE) 2025-08-27 EP claimed
US-12391819-B2 Fluoropolymer-based hybrid organic/inorganic composites SYENSQO SA (BE) 2025-08-19 US claimed
EP-3724939-B1 FLUOROPOLYMER MEMBRANE FOR ELECTROCHEMICAL DEVICES SYENSQO SA (BE) 2025-08-13 EP claimed
US-20240240069-A1 POLYMERIZATION OF A SILANE-MODIFIED POLYMER, WHICH IS PRODUCED BY MEANS OF A RADICAL CHAIN POLYMERIZATION, IN A POLYOL OR IN A PREPOLYMER WITH TERMINAL ISOCYANATE GROUPS, AND USE THEREOF IN POLYURETHANE FORMULATIONS FOLLMANN GMBH & CO. KG (DE) 2024-07-18 US claimed
US-11975125-B2 Medical devices MICROVENTION, INC. (US) 2024-05-07 US claimed
WO-2024083887-A1 FREE-RADICAL POLYMERISATION OF UV-CROSSLINKING SILANE ACRYLATES IN AN ISOCYANATE-CONTAINING POLYURETHANE MATRIX FOLLMANN GMBH & CO. KG (DE) 2024-04-25 WO claimed
EP-3860669-B1 MEDICAL DEVICES MICROVENTION INC (US) 2024-04-03 EP claimed
US-6248805-B1 THERMAL INK JET PRNTING HEWLETT-PACKARD COMPANY 2001-06-19 US claimed
US-6057384-A VEHICLE AND COLORANT ASSOCIATED WITH A PRIMER CORE/SHELL POLYMER; DURABLR SMEAR-FAST FILM HEWLETT-PACKARD COMPANY (US) 2000-05-02 US claimed
US-5990202-A DURABLE, SMEAR-FAST INK FILMS COMPRISING DUAL ENCAPSULATED COLORANT; A PRIMER CORE/SHELL POLYMER COATING A COLORANT (ADHESION) AND AN EXTERIOR CORE/SHELL POLYMER COATING FOR DURABILITY HEWLETT-PACKARD COMPANY (US) 1999-11-23 US claimed
US-5916964-A 40 TO 60 PERCENT OF A POLYTETRAMETHYLENE ETHER GLYCOL OR DERIVATIVE THEREOF, 1 TO 10 PERCENT OF A POLYETHER POLYOL, 0 TO 15 PERCENT OF A HYDROLYTICALLY STABLE POLYESTER POLYOL, 0.5 TO 3.0 PERCENT OF A SILANE, AND 10 TO 30 PERCENT BY WEIGHT OF REICHHOLD CHEMICALS, INC. (US) 1999-06-29 US claimed
EP-0593297-B1 Resin composition for coating and paint HITACHI CHEMICAL CO LTD (JP) 1997-04-16 EP claimed
US-5539051-A ACRYLATE RESIN AND ADDITION TYPE RESIN WITH PENDANT SILICON CONTAINING GROUPS, FOR CONCRETE, MASONRY, NONSTAINING HITACHI CHEMICAL COMPANY CO., LTD. (JP) 1996-07-23 US claimed
EP-0593297-A1 Resin composition for coating and paint HITACHI CHEMICAL CO., LTD. (JP) 1994-04-20 EP claimed
US-5021507-A Arcylic modified reactive urethane hot melt adhesive compositions NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1991-06-04 US claimed
EP-0224795-B1 REMOVABLE PRESSURE SENSITIVE ADHESIVE National Starch and Chemical Corporation (US) 1990-03-21 EP claimed
US-4716194-A SMALL AMOUNT OF SILANE MONOMER NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1987-12-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629657-B2 Lithium ion adsorbents ILK, SDC1, LAMTOR3 TSHR 3614/4885ALDH1A1 2379/4885CYP3A4 2811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.