SCHEMBL8465759

SCHEMBL8465759

O=P(O)(O)C1(P(=O)(O)O)CC2CCCNC2C1S

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9172962 0.82
SCHEMBL9177112 0.78 MEN1 (0.34) FDPS
SCHEMBL8467387 0.78
SCHEMBL8465246 0.72
SCHEMBL9227232 0.68 FDPS (0.31) FDPS
SCHEMBL8501088 0.68 FDPS (0.31) FDPS
SCHEMBL13224024 0.65 FDPS (0.31) FDPS
SCHEMBL3458961 0.65 FDPS (0.31) FDPS
SCHEMBL3459618 0.65 FDPS (0.31) FDPS
SCHEMBL3458975 0.65 FDPS (0.31) FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5869471-A Methods for the treatment of arthritis using phosphonates and NSAIDS THE PROCTOR & GAMBLE COMPANY (US) 1999-02-09 US claimed
EP-0650361-A1 COMPOSITIONS FOR THE TREATMENT OF ARTHRITIS CONTAINING PHOSPHONATES AND NSAIDS PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) 1995-05-03 EP claimed
WO-1994000130-A1 COMPOSITIONS FOR THE TREATMENT OF ARTHRITIS CONTAINING PHOSPHONATES AND NSAIDS PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) 1994-01-06 WO claimed
US-5763611-A TREATING OSTEOPOROSIS, RHEUMATOID ARTHRITIS THE PROCTER & GAMBLE COMPANY (US) 1998-06-09 US disclosed