Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9227232 | 0.93 | FDPS (0.31) | FDPS | |
| SCHEMBL27344885 | 0.86 | — | — | |
| SCHEMBL8610112 | 0.71 | MAPT (0.32) | FDPS | |
| SCHEMBL8467728 | 0.71 | — | — | |
| SCHEMBL8465550 | 0.70 | — | — | |
| SCHEMBL9740737 | 0.69 | TSHR (0.31) | — | |
| SCHEMBL8467818 | 0.69 | — | — | |
| SCHEMBL9172962 | 0.69 | — | — | |
| SCHEMBL8465759 | 0.68 | FDPS (0.31) | FDPS | |
| SCHEMBL27319724 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393746-A | Bone disorders | P&G PHARMACEUTICALS, INC. (US) | 1995-02-28 | — | — | US | claimed |
| US-5137880-A | Treatment for osteoporosis, pagents disease arthritis | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1992-08-11 | — | — | US | claimed |
| EP-0273514-B1 | NOVEL BICYCLIC DIPHOSPHONATE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS | Norwich Eaton Pharmaceuticals, Inc. (US) | 1990-12-12 | — | — | EP | claimed |
| EP-0273514-A1 | Novel bicyclic diphosphonate compounds and pharmaceutical compositions | Norwich Eaton Pharmaceuticals, Inc. (US) | 1988-07-06 | — | — | EP | claimed |
| EP-0643716-B1 | QUATERNARY NITROGEN-CONTAINING PHOSPHONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMA (US) | 1999-12-08 | — | — | EP | disclosed |
| US-5869471-A | Methods for the treatment of arthritis using phosphonates and NSAIDS | THE PROCTOR & GAMBLE COMPANY (US) | 1999-02-09 | — | — | US | disclosed |
| US-5763611-A | TREATING OSTEOPOROSIS, RHEUMATOID ARTHRITIS | THE PROCTER & GAMBLE COMPANY (US) | 1998-06-09 | — | — | US | disclosed |
| US-5753634-A | TREATING OR PREVENTING ARTHRITIS AND OSTEOPOROSIS | THE PROCTER & GAMBLE COMPANY (US) | 1998-05-19 | — | — | US | disclosed |
| EP-0650361-A1 | COMPOSITIONS FOR THE TREATMENT OF ARTHRITIS CONTAINING PHOSPHONATES AND NSAIDS | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1995-05-03 | — | — | EP | disclosed |
| EP-0643716-A1 | QUATERNARY NITROGEN-CONTAINING PHOSPHONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | THE PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1995-03-22 | — | — | EP | disclosed |
| EP-0642520-A1 | THIO-SUBSTITUTED CYCLIC PHOSPHONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS (US) | 1995-03-15 | — | — | EP | disclosed |
| US-5393746-A | Bone disorders | P&G PHARMACEUTICALS, INC. (US) | 1995-02-28 | — | — | US | disclosed |
| WO-1994000130-A1 | COMPOSITIONS FOR THE TREATMENT OF ARTHRITIS CONTAINING PHOSPHONATES AND NSAIDS | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1994-01-06 | — | — | WO | disclosed |
| WO-1993024499-A1 | QUATERNARY NITROGEN-CONTAINING PHOSPHONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1993-12-09 | — | — | WO | disclosed |
| WO-1993024497-A1 | THIO-SUBSTITUTED CYCLIC PHOSPHONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1993-12-09 | — | — | WO | disclosed |
| US-5137880-A | Treatment for osteoporosis, pagents disease arthritis | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1992-08-11 | — | — | US | disclosed |
| EP-0273514-B1 | NOVEL BICYCLIC DIPHOSPHONATE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS | Norwich Eaton Pharmaceuticals, Inc. (US) | 1990-12-12 | — | — | EP | disclosed |
| US-4868164-A | OSTEOPOROSIS, ARTHRITIS | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1989-09-19 | — | — | US | disclosed |
| EP-0273514-A1 | Novel bicyclic diphosphonate compounds and pharmaceutical compositions | Norwich Eaton Pharmaceuticals, Inc. (US) | 1988-07-06 | — | — | EP | disclosed |