Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29002972 | 0.87 | LMNA (0.33) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL8464103 | 0.87 | IKBKB (0.37) | IKBKBACLYALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL646150 | 0.84 | PTGER4 (0.35) | ALDH1A1TSHRMAPT | |
| SCHEMBL1358599 | 0.83 | TDP1 (0.44) | ACLYALDH1A1HSD17B10KDM4ETSHR | |
| SCHEMBL28274071 | 0.82 | HSD17B10 (0.48) | ALDH1A1HSD17B10HPGDKDM4EL3MBTL1 | |
| SCHEMBL1358050 | 0.82 | NPSR1 (0.34) | ACLYALDH1A1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL7949524 | 0.79 | ALDH1A1 (0.43) | ALDH1A1HSD17B10HPGDKDM4ETSHR | |
| SCHEMBL8465758 | 0.79 | KMT2A (0.34) | IKBKBALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL1356924 | 0.78 | ALDH1A1 (0.34) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| SCHEMBL17644154 | 0.78 | HSD17B10 (0.42) | ALDH1A1HSD17B10HPGDKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999021842-A1 | HERBICIDAL 4-BENZOYLISOXAZOLES DERIVATIVES | ZENECA LIMITED (GB) | 1999-05-06 | — | — | WO | disclosed |
| US-5863865-A | APPLYING PLANT GROWTH REGULATOR TO AN AREA WHERE SUCH CONTROL IS DESIRED | ZENECA LIMITED (GB) | 1999-01-26 | — | — | US | disclosed |
| EP-0639173-A1 | CERTAIN 2-(2'METHYL-3',4'-TRISUBSTITUTED BENZOYL)-1,3-CYCLOHEXANEDIONES | ZENECA LIMITED (GB) | 1995-02-22 | — | — | EP | disclosed |
| US-5329041-A | For herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-07-12 | — | — | US | disclosed |
| EP-0639173-A4 | CERTAIN 2-(2'METHYL-3',4'-TRISUBSTITUTED BENZOYL)-1,3-CYCLOHEXANEDIONES. | ZENECA LTD (GB) | 1993-09-17 | — | — | EP | disclosed |
| WO-1992012953-A1 | CERTAIN 2-(2'METHYL-3',4'-TRISUBSTITUTED BENZOYL)-1,3-CYCLOHEXANEDIONES | ZENECA LIMITED (GB) | 1992-08-06 | — | — | WO | disclosed |
| WO-1992012957-A1 | TRISUBSTITUTED BENZOIC ACID INTERMEDIATES | NGUYEN NHAN H (US) | 1992-08-06 | — | — | WO | disclosed |
| US-5110979-A | Trisubstituted benzoic acid intermediates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-05-05 | — | — | US | disclosed |