Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 3/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489225 | 0.86 | HPD (0.47) | HPDFLT1FLT4KDRGAA | |
| SCHEMBL8761919 | 0.83 | HPD (0.46) | HPDFLT1FLT4KDRALDH1A1 | |
| SCHEMBL8492322 | 0.80 | PPARD (0.43) | HPDALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL8492588 | 0.79 | HPD (0.51) | HPDFLT1FLT4KDRGAA | |
| SCHEMBL8494775 | 0.78 | MEN1 (0.52) | HPDFLT1FLT4KDRALDH1A1 | |
| SCHEMBL6594174 | 0.76 | NPC1 (0.40) | GAAALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL8495654 | 0.76 | HPD (0.53) | HPDFLT1FLT4KDRGAA | |
| SCHEMBL8763711 | 0.76 | KMT2A (0.38) | GAAALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL7454528 | 0.75 | GPBAR1 (0.34) | — | |
| SCHEMBL8489367 | 0.75 | HPD (0.52) | HPDFLT1FLT4KDRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999021842-A1 | HERBICIDAL 4-BENZOYLISOXAZOLES DERIVATIVES | ZENECA LIMITED (GB) | 1999-05-06 | — | — | WO | claimed |
| US-5863865-A | APPLYING PLANT GROWTH REGULATOR TO AN AREA WHERE SUCH CONTROL IS DESIRED | ZENECA LIMITED (GB) | 1999-01-26 | — | — | US | claimed |
| WO-1999021842-A1 | HERBICIDAL 4-BENZOYLISOXAZOLES DERIVATIVES | ZENECA LIMITED (GB) | 1999-05-06 | — | — | WO | disclosed |
| US-5863865-A | APPLYING PLANT GROWTH REGULATOR TO AN AREA WHERE SUCH CONTROL IS DESIRED | ZENECA LIMITED (GB) | 1999-01-26 | — | — | US | disclosed |