Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HPD | P32754 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8492588 | 0.81 | HPD (0.51) | MEN1KMT2AHPDMAPTALDH1A1 | |
| SCHEMBL8489225 | 0.79 | HPD (0.47) | MEN1KMT2AHPDMAPTALDH1A1 | |
| SCHEMBL8761919 | 0.78 | HPD (0.46) | MEN1KMT2AHPDMAPTALDH1A1 | |
| SCHEMBL8466191 | 0.78 | HPD (0.44) | MEN1KMT2AHPDMAPTALDH1A1 | |
| SCHEMBL3092594 | 0.78 | MEN1 (0.52) | MEN1KMT2AS1PR3S1PR1 | |
| SCHEMBL8495654 | 0.78 | HPD (0.53) | MEN1KMT2AHPDMAPTALDH1A1 | |
| SCHEMBL8489367 | 0.77 | HPD (0.52) | MEN1KMT2AHPDMAPTALDH1A1 | |
| SCHEMBL27626374 | 0.77 | MEN1 (0.51) | MEN1KMT2AS1PR3S1PR1 | |
| SCHEMBL8684025 | 0.73 | MEN1 (0.47) | MEN1KMT2AALDH1A1S1PR3S1PR1 | |
| SCHEMBL8492322 | 0.73 | PPARD (0.43) | MEN1KMT2AHPDMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |