SCHEMBL8466243

SCHEMBL8466243

C[Si](C)(C)OP(=O)(Oc1ccccc1)[Si](C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ SRC P12931 1/20 0.45
▸ L3MBTL1 Q9Y468 3/20 0.44
▸ TDP1 Q9NUW8 1/20 0.44
▸ KDM4E B2RXH2 2/20 0.40
▸ MEN1 O00255 3/20 0.39
▸ KMT2A Q03164 3/20 0.39
▸ LMNA P02545 1/20 0.39
▸ ALDH1A1 P00352 2/20 0.38
▸ HTT P42858 2/20 0.38
▸ PKM P14618 1/20 0.38
▸ HPGD P15428 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5482457 0.80 SRC (0.48) SRCL3MBTL1TDP1KDM4EMEN1
SCHEMBL4232716 0.80 SRC (0.48) SRCL3MBTL1TDP1KDM4EMEN1
Triphenyl Phosphate SCHEMBL30619666 0.78 CYP3A4 (0.47) SRCL3MBTL1TDP1KDM4EMEN1
SCHEMBL27715051 0.77 SRC (0.55) SRCL3MBTL1TDP1KDM4EALDH1A1
SCHEMBL29767782 0.77 SRC (0.45) SRCL3MBTL1TDP1KDM4EMEN1
SCHEMBL8465493 0.74 SRC (0.50) SRCL3MBTL1TDP1KDM4EMEN1
SCHEMBL8464201 0.73 TSHR (0.50) SRCKDM4EALDH1A1
SCHEMBL676524 0.72 SRC (0.58) SRCL3MBTL1TDP1KDM4EMEN1
SCHEMBL28437272 0.71 — —
SCHEMBL8463062 0.71 L3MBTL1 (0.55) SRCL3MBTL1TDP1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0742263-B1 Silyl phosphonate as stabilizing agent for polydiorganosiloxanes DOW CORNING (US) 1999-06-02 — — EP claimed
EP-0742263-A2 Silyl phosphate as stabilizing agent for polydiorganosiloxanes DOW CORNING CORPORATION (US) 1996-11-13 — — EP claimed
US-5481014-A HEAT RESISTANCE; SHELF LIFE DOW CORNING CORPORATION (US) 1996-01-02 — — US claimed
EP-0742263-B1 Silyl phosphonate as stabilizing agent for polydiorganosiloxanes DOW CORNING (US) 1999-06-02 — — EP disclosed
EP-0742263-A2 Silyl phosphate as stabilizing agent for polydiorganosiloxanes DOW CORNING CORPORATION (US) 1996-11-13 — — EP disclosed
US-5481014-A HEAT RESISTANCE; SHELF LIFE DOW CORNING CORPORATION (US) 1996-01-02 — — US disclosed
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