Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CETP | P11597 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29704034 | 0.79 | TSHR (0.70) | TSHRCETPMAOBFOLH1ALDH1A1 | |
| SCHEMBL8466243 | 0.73 | SRC (0.45) | ALDH1A1SRCKDM4E | |
| SCHEMBL3367142 | 0.71 | TSHR (0.63) | TSHRCETPMAOBFOLH1ALDH1A1 | |
| SCHEMBL389180 | 0.71 | TSHR (0.63) | TSHRCETPMAOBFOLH1ALDH1A1 | |
| SCHEMBL8361083 | 0.71 | TSHR (0.63) | TSHRCETPFOLH1ALDH1A1NR4A1 | |
| SCHEMBL206609 | 0.71 | TSHR (0.68) | TSHRCETPALDH1A1SRCPDPK1 | |
| SCHEMBL22758890 | 0.70 | ALDH1A1 (0.51) | TSHRCETPALDH1A1MAPK1 | |
| SCHEMBL9052892 | 0.69 | TSHR (0.55) | TSHRCETPMAOBFOLH1ALDH1A1 | |
| SCHEMBL3705675 | 0.69 | TSHR (0.65) | TSHRCETPFOLH1ALDH1A1NR4A1 | |
| SCHEMBL12746424 | 0.68 | TSHR (0.59) | TSHRCETPMAOBFOLH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742263-B1 | Silyl phosphonate as stabilizing agent for polydiorganosiloxanes | DOW CORNING (US) | 1999-06-02 | — | — | EP | claimed |
| EP-0742263-A2 | Silyl phosphate as stabilizing agent for polydiorganosiloxanes | DOW CORNING CORPORATION (US) | 1996-11-13 | — | — | EP | claimed |
| US-5481014-A | HEAT RESISTANCE; SHELF LIFE | DOW CORNING CORPORATION (US) | 1996-01-02 | — | — | US | claimed |
| EP-0742263-B1 | Silyl phosphonate as stabilizing agent for polydiorganosiloxanes | DOW CORNING (US) | 1999-06-02 | — | — | EP | disclosed |
| EP-0742263-A2 | Silyl phosphate as stabilizing agent for polydiorganosiloxanes | DOW CORNING CORPORATION (US) | 1996-11-13 | — | — | EP | disclosed |
| US-5481014-A | HEAT RESISTANCE; SHELF LIFE | DOW CORNING CORPORATION (US) | 1996-01-02 | — | — | US | disclosed |