SCHEMBL8466529

SCHEMBL8466529

Nc1ccc(C(c2ccc(O)cc2)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.78
ESR2 Q92731 6/20 0.78
CYP3A4 P08684 2/20 0.56
HSD17B10 Q99714 2/20 0.56
ALDH1A1 P00352 1/20 0.56
CA3 P07451 1/20 0.56
THRB P10828 1/20 0.56
ALOX15 P16050 1/20 0.56
CA6 P23280 1/20 0.56
CASP1 P29466 1/20 0.56
HIF1A Q16665 1/20 0.56
CA14 Q9ULX7 1/20 0.56
APP P05067 3/20 0.45
KIF11 P52732 2/20 0.45
CYP19A1 P11511 2/20 0.39
LMNA P02545 1/20 0.39
TYR P14679 1/20 0.39
AR P10275 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3686864 0.89 ESR1 (1.00) ESR1ESR2CYP3A4HSD17B10ALDH1A1
SCHEMBL4560440 0.89 ESR1 (1.00) ESR1ESR2CYP3A4HSD17B10ALDH1A1
SCHEMBL21027 0.89 ESR1 (1.00) ESR1ESR2CYP3A4HSD17B10ALDH1A1
SCHEMBL10493869 0.89 ESR1 (0.56) ESR1ESR2CYP3A4HSD17B10ALDH1A1
SCHEMBL203678 0.89 ESR1 (0.56) ESR1ESR2CYP3A4HSD17B10ALDH1A1
SCHEMBL107817 0.89 ESR1 (0.56) ESR1ESR2CYP3A4HSD17B10ALDH1A1
SCHEMBL30625966 0.86 ESR1 (0.95) ESR1ESR2CYP3A4HSD17B10ALDH1A1
Hydrochloric Acid SCHEMBL8642415 0.86 ESR1 (0.54) ESR1ESR2CYP3A4ALDH1A1ALOX15
Ammonia Solution, Strong SCHEMBL3258090 0.86 ESR1 (0.54) ESR1ESR2CYP3A4HSD17B10ALDH1A1
Potassium SCHEMBL30701764 0.86 ESR1 (0.95) ESR1ESR2CYP3A4HSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108948353-B Preparation method of atomic oxygen resistant polyimide material 义乌市诠铈新材料有限公司 2020-12-04 CN claimed
CN-108948353-B Preparation method of atomic oxygen resistant polyimide material 义乌市诠铈新材料有限公司 2020-12-04 CN disclosed
CN-108948353-B Preparation method of atomic oxygen resistant polyimide material 义乌市诠铈新材料有限公司 2020-12-04 CN disclosed
CN-108948353-A A kind of preparation method of anti-atomic oxygen polyimides new material 王金桢 2018-12-07 CN disclosed
CN-108948353-A A kind of preparation method of anti-atomic oxygen polyimides new material 王金桢 2018-12-07 CN disclosed
EP-0659802-B1 Polyimide MITSUI CHEMICALS INC (JP) 1999-03-17 EP disclosed
EP-0478321-B1 Photosenstive resin composition for forming polyimide film pattern and method of forming polyimide film pattern TOSHIBA KK (JP) 1997-11-12 EP disclosed
US-5631377-A LONG-CHAIN AROMATIC DIAMINE MONOMER; MELT PROCESSABILITY, HEAT RESISTANCE MITSUI TOATSU CHEMICALS, INC. (JP) 1997-05-20 US disclosed
US-5518864-A PHOTOSENSITIVE, QUINONE DIAZIDE KABUSHIKI KAISHA TOSHIBA (JP) 1996-05-21 US disclosed
US-5508377-A IMPROVED PROCESSABILITY, HEAT RESISTANCE; ELECTRONICS, STRUCTURAL MATERIALS MITSUI TOATSU CHEMICALS, INC. (JP) 1996-04-16 US disclosed
EP-0431971-B1 Photosensitive composition and resin-encapsulated semiconductor device TOSHIBA KK (JP) 1995-07-19 EP disclosed
EP-0659802-A1 Polyimide MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-06-28 EP disclosed
US-5348835-A Without photoresist KABUSHIKI KAISHA TOSHIBA (JP) 1994-09-20 US disclosed
US-5340684-A Polyimidesiloxane copolymers KABUSHIKI KAISHA TOSHIBA (JP) 1994-08-23 US disclosed
EP-0478321-A1 Photosenstive resin composition for forming polyimide film pattern and method of forming polyimide film pattern KABUSHIKI KAISHA TOSHIBA (JP) 1992-04-01 EP disclosed
EP-0431971-A2 Photosensitive composition and resin-encapsulated semiconductor device KABUSHIKI KAISHA TOSHIBA (JP) 1991-06-12 EP disclosed