Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GALR1 | P47211 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | CTSA | P10619 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20530677 | 0.87 | TP53 (0.46) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL20530663 | 0.85 | MAPT (0.47) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7823524 | 0.85 | RAB9A (0.48) | NPC1MAPTRAB9APOLB | |
| SCHEMBL7575014 | 0.84 | KDM4E (0.47) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL20530634 | 0.84 | NPC1 (0.47) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28329380 | 0.83 | ALDH1A1 (0.44) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL30418797 | 0.83 | GRM5 (0.53) | ALDH1A1NPC1MAPTRAB9AHPGD | |
| SCHEMBL7571121 | 0.83 | KDM4E (0.50) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7570097 | 0.82 | JMJD6 (0.48) | ALDH1A1MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7571031 | 0.82 | MAPT (0.49) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5964919-A | STABILIZING THE ACTIVE ZINC BY SUSPENDING IN A CONTAINER WITH AN SOLVENT SELECT FROM ETHER, HYDROCARBON, AROMATIC HYDROCARABON OR APROTIC SOLVENT UNDER INERT GAS, SEALING THE CONTAINER | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1999-10-12 | — | — | US | disclosed |
| US-5756653-A | REACTING A REDUCING AGENT ON A ZINC SALT | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1998-05-26 | — | — | US | disclosed |
| US-5358546-A | Reacting a zinc compound with a reducting agent | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1994-10-25 | — | — | US | disclosed |
| WO-1993015086-A1 | HIGHLY REACTIVE FORMS OF ZINC AND REAGENTS THEREOF | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1993-08-05 | — | — | WO | disclosed |