Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | FABP7 | O15540 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30229529 | 0.77 | MDM4 (0.51) | CASP3 | |
| SCHEMBL18795729 | 0.77 | MDM4 (0.51) | CASP3 | |
| SCHEMBL27749256 | 0.77 | MDM4 (0.51) | CASP3 | |
| SCHEMBL850332 | 0.77 | MDM4 (0.51) | CASP3 | |
| SCHEMBL30229718 | 0.77 | MDM4 (0.51) | CASP3 | |
| SCHEMBL27312034 | 0.77 | MAPT (0.54) | ALDH1A1KDM4EMAPTGAACASP1 | |
| SCHEMBL5925150 | 0.77 | MAPT (0.54) | ALDH1A1KDM4EMAPTGAACASP1 | |
| SCHEMBL7811480 | 0.77 | MAPT (0.54) | ALDH1A1KDM4EMAPTGAACASP1 | |
| SCHEMBL5035599 | 0.76 | KMT2A (0.40) | ALDH1A1MAPTKMT2ACASP3FABP7 | |
| SCHEMBL3855559 | 0.76 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTGAACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955421-A | OXIDATION RESISTANCE; ENHANCING GROWTH HORMONE RELEASE | MEDIOLANUM PHARMACEUTICALS LIMITED (IE) | 1999-09-21 | — | — | US | disclosed |
| US-5872100-A | Peptides containing D-2-Alkyl-Tryptophan | ARDANA BIOSCIENCE LIMITED (GB) | 1999-02-16 | — | — | US | disclosed |
| US-5668254-A | BIOACTIVE, OXIDATION RESISTANCE | Deghenghi, Romano (CH) | 1997-09-16 | — | — | US | disclosed |
| US-5646301-A | INCORPORATION INTO PEPTIDES | Deghenghi, Romano (CH) | 1997-07-08 | — | — | US | disclosed |
| US-5635379-A | PREPARED FROM N-ALPHA-ACETYL-2-ALKYL TRYPTOPHAN RACEMIC MIXTURE | Deghenghi, Romano (CH) | 1997-06-03 | — | — | US | disclosed |