SCHEMBL8466752

SCHEMBL8466752

CC1CCCCN(C(=O)CCCCC(N)=O)C1(C)C

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.36
NPC1 O15118 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
GNAI3 P08754 1/20 0.33
GNAO1 P09471 1/20 0.33
GNAI1 P63096 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
ATM Q13315 1/20 0.33
NAAA Q02083 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17907450 0.72 HPGD (0.37) MAPT
SCHEMBL1160170 0.69 GAA (0.50) L3MBTL1
SCHEMBL28399941 0.68 KMT2A (0.34) MEN1KMT2ANAAA
SCHEMBL8466757 0.68 NPC1 (0.33) NPC1MEN1KMT2AGNAI3GNAO1
SCHEMBL12498926 0.67 SMN1; SMN2 (0.31)
SCHEMBL729631 0.66 ATM (0.74) L3MBTL1MEN1KMT2ATDP1GNAI3
SCHEMBL9329431 0.65 KMT2A (0.37) L3MBTL1NPC1KMT2AGNAI3GNAO1
SCHEMBL1159944 0.65 KMT2A (0.74) L3MBTL1NPC1MEN1KMT2ATDP1
Adipic Acid SCHEMBL28204727 0.65 SMN1; SMN2 (0.40) MEN1KMT2ATDP1
SCHEMBL11769367 0.64 ATM (0.71) L3MBTL1MEN1KMT2ATDP1GNAI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5925300-A ADDING A WATER SOLUBLE ADDITIVES COMPRISING CALCIUM, MAGNESIUM, OR ZINC SALTS OF DICARBOXYLIC ACIDS TO POLYMER BEFORE FORMING FIBER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-07-20 US disclosed
EP-0736063-B1 NYLON CONTAINING NUCLEATION ADDITIVES DU PONT (US) 1999-06-02 EP disclosed
US-5654355-A NYLON POLYMER CONTAINING WATER SOLUBLE MAGNESIUM, CALCIUM OR ZINC SALT OF ADIPIC ACID, FREE OF FLUORIDE AND MONOCARBOXYLIC ACIDS OR SALTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-08-05 US disclosed
EP-0736063-A1 NYLON CONTAINING NUCLEATION ADDITIVES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-10-09 EP disclosed
WO-1995017462-A1 NYLON CONTAINING NUCLEATION ADDITIVES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-06-29 WO disclosed