SCHEMBL8466757

SCHEMBL8466757

CC1CCCCC(C)(C)N1C(=O)CCCCC(N)=O

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.33
GNAI3 P08754 1/20 0.31
GNAO1 P09471 1/20 0.31
GNAI1 P63096 1/20 0.31
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
ACE P12821 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6268858 0.71 ALDH1A1 (0.40) MEN1POLBKMT2A
SCHEMBL1160171 0.69 GAA (0.47) MAPT
SCHEMBL28399941 0.68 KMT2A (0.34) MEN1KMT2A
SCHEMBL8466752 0.68 L3MBTL1 (0.36) NPC1GNAI3GNAO1GNAI1MEN1
SCHEMBL28786674 0.67 SMN1; SMN2 (0.47) NPC1GNAI3GNAO1GNAI1MEN1
SCHEMBL9329431 0.65 KMT2A (0.37) NPC1GNAI3GNAO1GNAI1KMT2A
SCHEMBL2280917 0.62 ATM (0.67) NPC1GNAI3GNAO1GNAI1MEN1
SCHEMBL3591811 0.62 L3MBTL1 (0.44) ACE
SCHEMBL7511094 0.62 GAA (0.35) NPC1GNAI3GNAO1GNAI1
SCHEMBL1027714 0.62 L3MBTL1 (0.48) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5925300-A ADDING A WATER SOLUBLE ADDITIVES COMPRISING CALCIUM, MAGNESIUM, OR ZINC SALTS OF DICARBOXYLIC ACIDS TO POLYMER BEFORE FORMING FIBER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-07-20 US disclosed
EP-0736063-B1 NYLON CONTAINING NUCLEATION ADDITIVES DU PONT (US) 1999-06-02 EP disclosed
US-5654355-A NYLON POLYMER CONTAINING WATER SOLUBLE MAGNESIUM, CALCIUM OR ZINC SALT OF ADIPIC ACID, FREE OF FLUORIDE AND MONOCARBOXYLIC ACIDS OR SALTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-08-05 US disclosed
EP-0736063-A1 NYLON CONTAINING NUCLEATION ADDITIVES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-10-09 EP disclosed
WO-1995017462-A1 NYLON CONTAINING NUCLEATION ADDITIVES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-06-29 WO disclosed