SCHEMBL8466780

SCHEMBL8466780

FC(Cl)(C(Cl)(Cl)Cl)C(Cl)(Cl)Cl

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
CYP2E1 P05181 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10706412 0.80
SCHEMBL865475 0.80
SCHEMBL8677456 0.80
SCHEMBL710881 0.74 LMNA (0.30) LMNA
SCHEMBL63592 0.71
SCHEMBL1221821 0.71
SCHEMBL74196 0.71
SCHEMBL8675385 0.70
SCHEMBL8132063 0.68
Dichlorodifluoromethane SCHEMBL485 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5880317-A Preparation of 1,1,2,3,3-pentafluoropropane ALLIEDSIGNAL INC. (US) 1999-03-09 US claimed
US-4438088-A Preparation of antimony trifluorodichloride and fluorination of fluorinatable hydrocarbons and halocarbons therewith THE DOW CHEMICAL COMPANY (US) 1984-03-20 US claimed
EP-2554530-B2 METHOD FOR PRODUCING 3-CHLORO-PENTAFLUOROPROPENE DAIKIN IND LTD (JP) 2019-06-12 EP disclosed
EP-2554530-B1 METHOD FOR PRODUCING 3-CHLORO-PENTAFLUOROPROPENE DAIKIN IND LTD (JP) 2016-07-13 EP disclosed
CN-102834366-B Method for producing 3-chloro-pentafluoropropene DAIKIN IND LTD 2015-03-18 CN disclosed
US-8816138-B2 Method for producing 3-chloro-pentafluoropropene DAIKIN INDUSTRIES, LTD. (JP) 2014-08-26 US disclosed
EP-2554530-A1 METHOD FOR PRODUCING 3-CHLORO-PENTAFLUOROPROPENE Daikin Industries, Ltd. (JP) 2013-02-06 EP disclosed
US-20130023704-A1 METHOD FOR PRODUCING 3-CHLORO-PENTAFLUOROPROPENE DAIKIN INDUSTRIES, LTD. (JP) 2013-01-24 US disclosed
CN-102834366-A Method for producing 3-chloro-pentafluoropropene DAIKIN IND LTD 2012-12-19 CN disclosed
EP-0407622-B1 PROCESS FOR PRODUCING A 2,2-DIFLUOROPROPANE ASAHI GLASS CO LTD (JP) 1996-12-04 EP disclosed
US-5315048-A Preparation of 1,1,1,2,3-pentafluoropropane by reduction of 1,2,3-trichloropentafluropropane ALLIEDSIGNAL INC. (US) 1994-05-24 US disclosed
US-5264639-A Fluorination of chlorine containing 2,2-halogenopropane with hydrogen fluoride ASAHI GLASS COMPANY LTD. (JP) 1993-11-23 US disclosed
EP-0407622-A1 PROCESS FOR PRODUCING A 2,2-DIFLUOROPROPANE. ASAHI GLASS CO LTD (JP) 1991-01-16 EP disclosed
WO-1990008754-A2 PROCESS FOR PRODUCING A 2,2-DIFLUOROPROPANE ASAHI GLASS COMPANY LTD. (JP) 1990-08-09 WO disclosed
US-4438088-A Preparation of antimony trifluorodichloride and fluorination of fluorinatable hydrocarbons and halocarbons therewith THE DOW CHEMICAL COMPANY (US) 1984-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130023704-A1 METHOD FOR PRODUCING 3-CHLORO-PENTAFLUOROPROPENE PFAS, FFAR3, NOTUM ALDH1A1 2801/4885LMNA 4316/4885CYP2E1 667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.