Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 2/20 | 0.87 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.87 |
| ▸ | MEN1 | O00255 | 1/20 | 0.87 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.87 |
| ▸ | POLB | P06746 | 1/20 | 0.87 |
| ▸ | GAA | P10253 | 1/20 | 0.87 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.87 |
| ▸ | HPGD | P15428 | 1/20 | 0.87 |
| ▸ | TSHR | P16473 | 1/20 | 0.87 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.87 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.87 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.87 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.87 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.65 |
| ▸ | DHFR | P00374 | 7/20 | 0.59 |
| ▸ | GART | P22102 | 2/20 | 0.59 |
| ▸ | ATIC | P31939 | 2/20 | 0.59 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.53 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Folic Acid SCHEMBL27601535 | 1.00 | TYMS (0.87) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL991371 | 1.00 | TYMS (0.87) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL8956351 | 0.95 | TYMS (0.89) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL975173 | 0.95 | TYMS (0.89) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL23219019 | 0.95 | TYMS (0.92) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL706319 | 0.95 | TYMS (0.92) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL27857798 | 0.93 | TYMS (0.91) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL248712 | 0.93 | TYMS (1.00) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL332170 | 0.93 | TYMS (1.00) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL403054 | 0.93 | TYMS (1.00) | TYMSKDM4EMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6008221-A | REDUCING HOMOCYSTEINE IN BLOOD LEVEL ON THE VASCULATURE OR ON NERVE CELLS IN THE BRAIN, DETOXIFICATION, TREATING NEURODEGENERATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-12-28 | — | — | US | disclosed |