Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.36 |
| ▸ | YTHDC1 | Q96MU7 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8467319 | 0.91 | HDAC1 (0.37) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL8467135 | 0.88 | TAAR1 (0.42) | P2RY1 | |
| SCHEMBL8464251 | 0.83 | ADCY5 (0.36) | HDAC6 | |
| SCHEMBL8466905 | 0.83 | ADCY5 (0.36) | HDAC6 | |
| SCHEMBL8467074 | 0.81 | P2RY1 (0.43) | HDAC1HDAC2P2RY1YTHDC1 | |
| SCHEMBL8464285 | 0.81 | P2RY1 (0.43) | HDAC1HDAC2P2RY1YTHDC1 | |
| SCHEMBL8466600 | 0.81 | ADCY5 (0.47) | — | |
| SCHEMBL8465859 | 0.81 | ADCY5 (0.47) | — | |
| SCHEMBL8466911 | 0.81 | ADCY5 (0.37) | HDAC1HDAC2P2RY1 | |
| SCHEMBL8467662 | 0.80 | ADCY5 (0.36) | HDAC1HDAC2P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994361-A | ANTITUMOR, ANTICANCER AGENT | BIOCHEM PHARMA (CA) | 1999-11-30 | — | — | US | claimed |